胸腺瘤Masaoka分期与CT特征相关性分析

doi:10.12117/jccmi.2019.10.003

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Abstract Objective: To explore the value of preoperative CT to predict Masaoka staging system of thymoma. Methods: The basic data of 109 patients with pathologically confirmed thymoma were retrospectively analyzed and grouped according to Masaoka staging. The CT features of density, morphology, calcification, margin, enhancement, necrosis, lymph node metastasis, peripheral invasion, tumor diameter and pleural dissemination were compared between the groups. Logistic regression analysis was performed on the features, and the diagnostic value was also evaluated by an ROC curve. Results: Of the 109 patients with thymoma, 22(20.18%) were in stage Ⅰ, 31(28.44%) in stage Ⅱ, 45(41.29%) in stage Ⅲ, 8(7.34%) in stage Ⅳa, and 3(2.75%) in stage Ⅳb. Multivariate Logistic regression analysis showed the uneven density(OR=4.031, 95%CI: 1.137~14.293, P=0.031), marginal smoothness(OR=4.245, 95%CI: 1.276~14.122, P=0.018), and uneven enhancement(OR=7.284, 95%CI: 1.288~41.189, P=0.025), extravasation(OR=15.349, 95% CI: 3.531~66.723, P<0.001), tumor diameter≥62 mm(OR=3.944, 95%CI: 1.196~13.002, P=0.024) and pleural dissemination(OR=17.288, 95%CI: 1.216~245.707, P=0.035) were correlated with Masaoka Ⅲ and Ⅳ, and the area under the ROC curve was 0.910. Conclusion: CT features of thymomas correlated well with Masaoka staging, which will help predict progression of thymoma and adjuvant therapy before operation.

Key words： Thymoma Tomography, X-ray computed

Received: 16 October 2018

PACS:	Ｒ734.5
	Ｒ814.42

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	Articles by authors
	WANG Heng-qiang
	HUANG Zhuang-shi
	LI Rong-yao
	ZHANG Wen-qiang
	YANG Xi-bin

Cite this article:

WANG Heng-qiang,HUANG Zhuang-shi,LI Rong-yao, et al. Correlation analysis between Masaoka staging and CT features of thymoma[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2019, 30(10): 694-697.

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http://www.jccmi.com.cn/EN/10.12117/jccmi.2019.10.003 OR http://www.jccmi.com.cn/EN/Y2019/V30/I10/694

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