MRI增强全域灰度直方图在鉴别儿童后颅窝肿瘤的应用

doi:10.12117/jccmi.2019.03.001

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Abstract Objective: To study the value of whole tumors enhanced MRI gray histogram analysis of differential diagnosis in three common pediatric posterior fossa tumors(ependymoma, astrocytoma, medulloblastoma). Methods: A retrospective analysis was conducted by brain MRI examination and pathology diagnosis of 76 cases of posterior fossa tumors in children in our hospital. Among them, there were 25 cases of ependymoma, 26 cases of astrocytoma, 25 cases of medulloblastoma. Respectively, we drew the region of interest(ROI) in the enhanced MR sagittal images of three groups on each layer of tumor level by using Mazda software and analyzed the whole tumors gray histogram, then performed statistical analysis on the three sets of parameters obtained from histograms to find out statistical difference of each parameter. Results: Through histogram analysis of 9 parameters, the difference of these 6 parameters were statistically significant(all P<0.05), including mean, variance, skewness, Perc.10%, Perc.50% and Perc.99%, the remaining 3 parameters, including kurtosis, Perc.01%, Perc.90% had no significant difference(all P>0.05). Conclusion: The MRI gray histogram analysis based on whole tumors is helpful for the identification of three kinds of pediatric posterior fossa tumors，the Perc.50% and variance had a high diagnostic efficiency.

Key words： Ependymoma Astrocytoma Medulloblastoma Child Magnetic resonance imaging

Received: 16 March 2018

PACS:	Ｒ739.41
	R730.264
	Ｒ445.2

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	Articles by authors
	XU Ke
	ZHANG Yong
	CHENG Jing-liang
	ZHU Chen-di
	WANG Wei-jian

Cite this article:

XU Ke,ZHANG Yong,CHENG Jing-liang, et al. Application of whole-tumor histogram analysis of enhanced MRI for posterior fossa tumors in children[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2019, 30(3): 153-157.

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http://www.jccmi.com.cn/EN/10.12117/jccmi.2019.03.001 OR http://www.jccmi.com.cn/EN/Y2019/V30/I3/153

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