基于CT双气相扫描对COPD患者肺容积定量研究

doi:10.12117/jccmi.2019.09.003

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Abstract Objective: To explore the clinical value of quantitative measurement of lung volume by CT in normal people and chronic obstructive pulmonary disease(COPD) based on quantitative analysis of lung volume by digital lung test platform. Methods: Dual-phase chest CT data of 91 cases of healthy people and 61 cases of COPD from November 2016 to February 2018 were collected. 128-slice spiral CT was used for dual-phase chest scan. The images were imported into the digital lung test platform for analysis. SPSS 20.0 was used for statistical analysis software. Results: The difference in double-phase lung volume of COPD was statistically significant(P＜0.01), and the inspiratory lung volume(LVin) >expiratory lung volume(LVex). The difference in double-phase lung volume between COPD group and normal group was statistically significant(P＜0.01), and the lung lobe volume of normal group was significantly smaller than that of COPD group. Quantitative analysis of dual-phase lung volume in each lung of normal group and COPD group: The difference of lung volume in both inspiratory or expiratory phases was most significant in the left upper lobe(the inspiratory lung volume difference was about (506.57±119.39) mL, the expiratory difference was about (468.74±111.2) mL), the difference of the right middle lobe was the smallest(the difference in lung volume was about (115.45±36.07) mL). Conclusion: CT quantitative measurement can determine the severity of each lung lesions. On the one hand, it has certain clinical diagnostic value for patients with COPD, and the expiratory phase can assist inspiratory phase to evaluate the severity of COPD lesions, on the other hand, it can provides effective clinical value for the evaluation of lung volume reduction surgery.

Key words： Pulmonary disease, chronic obstructive Lung volume measurements Tomography, spiral computed

Received: 05 September 2018

PACS:	Ｒ563
	Ｒ814.42

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	Articles by authors
	WANG Lei
	ZHAO Fan-hui
	LI Jian-long
	HUANG Xiao-qi

Cite this article:

WANG Lei,ZHAO Fan-hui,LI Jian-long, et al. Quantitative study of lung volume in patients with chronic obstructive pulmonary disease based on#br# CT dual-phase scanning[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2019, 30(9): 617-620.

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http://www.jccmi.com.cn/EN/10.12117/jccmi.2019.09.003 OR http://www.jccmi.com.cn/EN/Y2019/V30/I9/617

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