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| Imaging features and relevant pathological changes of dermatofibrosarcoma protuberans |
| FENG Hai-xia1, GU Long2, FENG Wei-hua1, WANG Wei-wei3, AN Li-hua3 |
1． Department of Radiology, Affiliated Hospital of Qingdao University, Qingdao Shandong 266003, China;
2． Department of Radiology, Jining Hospital of Traditional Chinese Medicine, Jining Shandong 272000, China;
3. Department of Radiology, Affiliated Hospital of Jining Medical University, Jining Shandong 272029, China |
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Abstract Objective: To investigate the CT and MRI features and relevant pathological features of dermatofibrosarcoma protuberans(DFSP), so as to improve the level of diagnosis of this disease. Methods: The CT and MRI findings and pathological results of 16 cases with DFSP proved by pathology were retrospectively analyzed. Results: Fifteen cases were located in the skin or subcutaneous tissues and 1 case under the superficial fascia, which 4 cases occurred in the pelvic wall, 4 cases in the abdominal wall, 3 cases in the head and neck, 3 cases in the thighs, 1 case in the breast and 1 case in the scrotum. Eight cases were round-like shapes, 7 cases were irregular shapes, of which 6 cases were complicated with “nodular protruded outward”, 1 case was fusiform. The maximum diameter of tumors was 2.9~10 cm, with an average of 5.6 cm. The boundaries of the tumors were not clear. On CT plain scan, 4 cases showed homogeneous low-density, CT values were about 23~37 HU, of which 1 case was homogeneous enhancement. On T1WI, 11 cases showed slightly hypointensity, 1 case showed isointensity. On T2WI, 4 cases displayed homogeneous hyperintensity, 8 cases showed inhomogeneous hyperintensity, 7 cases showed hyperintensity on DWI, 5 cases presented heterogenous enhancement. 14 cases showed “fat tail sign”, 12 cases showed “skin tail sign”, and 10 cases showed “fascia tail sign”. Under the microscope, spindle shaped tumor cells arranged in a curved pattern around the blood vessels and infiltrated in the dermis and subcutaneous tissue. There was mucoid matrix in the parenchyma in 1 case, 1 case with fibrosarcoma-like area, 1 case with mucous area and fibrosarcoma-like area. The immunohistochemical reports of all cases were positive for CD34. Conclusion: The imaging manifestations of DFSP have certain characteristics, which can provide reference for preoperative diagnosis and operation mode formulation. The final diagnosis still needs pathological and immunohistochemical examination.
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Received: 07 September 2018
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2019, Vol. 30 
