成人颞叶癫痫患者发作间期18F-FDG PET/CT脑代谢显像与术后疗效的关系

doi:10.12117/jccmi.2020.02.003

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Abstract Objective: To investigate the relationship between interictal 18F-FDG PET/CT image pattern and prognosis of adult patients with adult temporal lobe epilepsy. Methods: A retrospective analysis from August 2013 to March 2018 was made for patients undertaking interictal brain 18F-FDG PET/CT. There were 62 cases in total, including 22 cases(35.48%) of women and 40 cases(64.52%) of men, age range 18～58(31.48±10.48) years. According to the number of lesions(single/multiple),side(ipsilateral/bilateral), PET/CT image could be divided into one single low metabolic lesion group, low unilateral multiple metabolic lesions on the same side and double side. According to Engel grading, the patients were divided into 45 cases(72.58%) in the satisfactory efficacy group(Engel Ⅰ) and 17 cases(27.42%) in the unsatisfactory efficacy group(Engel Ⅱ+Engel Ⅲ+Engel Ⅳ). Univariate analysis was performed on the number and side of lesions on PET/CT, and Logistic regression analysis was performed on the factors with statistical significance, to summarize the relationship between the metabolic change pattern of 18F-FDG PET/CT and the postoperative prognosis of adult patients with temporal lobe epilepsy. Result: The results of univariate analysis showed that the number and side of lesions were statistically significant(P values were 0.001 and 0.02, respectively). Logistic regression analysis showed that the number of lesions was strongly correlated with the prognosis(OR=7.219, 95%CI: 0.339~8.676, P=0.008), while the number of lesions was not correlated with the prognosis(OR=1.714, 95%CI: 1.691~30.809, P=0.515). Conclusion: 18F-FDG PET/CT brain metabolism imaging can be used to predict the postoperative efficacy of adult patients with temporal lobe epilepsy. Patients with single low-metabolism lesions have better surgical efficacy, and the number of low-metabolism lesions is an independent predictor of surgical prognosis.

Key words： Epilepsy, temporal lobe Positron-emission tomography Tomography, X-ray computed

Received: 21 May 2019

PACS:	Ｒ742.1
	Ｒ817.4
	Ｒ814.42

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	Articles by authors
	LU Ling-ling
	CHEN Yu-feng
	GUO Jia
	WANG Zhi-guo
	ZHAN Ying
	WU Xiao-dan
	ZHANG Guo-xu

Cite this article:

LU Ling-ling,CHEN Yu-feng,GUO Jia, et al. The relationship between interictal 18F-FDG PET/CT image pattern and prognosis of adult patients with temporal lobe epilepsy[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2020, 31(2): 87-91.

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http://www.jccmi.com.cn/EN/10.12117/jccmi.2020.02.003 OR http://www.jccmi.com.cn/EN/Y2020/V31/I2/87

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