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| Study on changes in paraments of diffusion tensor imaging with lumbar disc herniation before and after discectomy |
| CUI Ting-ting1, YUE Yun-long1, JIN Yan-fang1, ZUO Li-li1, REN Jie1, LI Song-bai2 |
1. Department of MR, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China;
2. Department of Radiology, the First Hospital of China Medical University, Shenyang 110001, China |
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Abstract Objective: To investigate the changes of paraments of compressed nerve roots on diffusion tensor imaging(DTI) such as fractional anisotropy(FA) and apparent diffusion coefficient(ADC) in patients with single lumbar disc herniation before and after discectomy and the relationship between the paraments and the duration of symptoms. Methods: A total of 25 patients with percutaneous transforaminal endoscopic discectomy underwent DTI scanning before and three months after surgery. The FA and ADC values of the compressed and intact nerves were measured. Record the duration of symptoms and analyze the correlation between paraments and the duration. Results: The FA values of the compressed nerve roots were lower than intact nerves(P=0.000); The FA values increased at three months after surgical treatment(P=0.000), but they were still lower than intact nerves(P=0.038). The ADC values decreased at three months after surgical treatment(P=0.019), but no significant difference was found between the compressed and normal sides before and after surgery(P>0.05). There was a strong negative correlations between the difference of FA values of the compressed nerve roots before and after surgery and the duration of symptoms(r=-0.751, P=0.000). Conclusion: DTI may be an important tool to evaluate the structural changes of nerve roots in patients with lumbar disc herniation and that may has very important guiding significance in the clinical treatment.
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Received: 11 October 2019
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