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| The diagnostic value of DWI combined with DCE-MRI in staging of prostate cancer |
| SUN Jing, AO Wei-qun, GENG He, WU Yu, SHI Wei-ya, YU Jing-jing |
| Shanghai Putuo People’s Hospital, Shanghai 200060, China |
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Abstract Objective: To explore the diagnostic value of diffusion weighted imaging(DWI) and magnetic resonance dynamic contrast-enhanced imaging(DCE-MRI) in the staging of prostate cancer. Materials and Methods: DWI and DCE-MRI data of 48 cases of pathologically proved prostate cancer was retrospectively analyzed, and correlated with pathology and tumor staging． Results: Of the 48 cases, DWI and DCE-MRI diagnosed 11 cases of stage ≤B, 23 cases of stage C and 14 cases of stage D. The accuracy of tumor staging was 85.4%. The mean apparent diffusion coefficient(ADC) values of the tumor regions were (0.85±0.15)×10-3 mm2/s, (0.73±0.13)×10-3 mm2/s and (0.64±0.09)×10-3 mm2/s, respectively. There was statistical significance among the three stages(F=8.06, P<0.05). Spearman correlation analysis showed the ADC values in cancerous regions were negatively correlated with tumor staging(r=-0.53, P<0.01). Conclusions: The accuracy of ADC and DCE-MRI is high in staging of prostate cancer, and ADC combined with DCE-MRI might be useful to the staging of prostate cancer.
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Received: 08 July 2014
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2014, Vol. 25 
