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| Dynamic observation of aortic restenosis in rabbits by contrast-enhanced ultrasonography and common ultrasonography |
| LIU Qiu-ying1, REN Wei-dong1, TANG Bo2 |
| 1． Department of Heart Function, First Affiliated Hospital of China Medical University, Shenyang 110001, China; 2． Department of Vascular Surgery, First Hospital of Harbin Medical University, Harbin 150080, China |
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Abstract Objective: To compare the value of contrast-enhanced ultrasonography(CEUS) and common ultrasonography in follow-up of aortic restenosis in rabbits after balloon injury and to find a new method to observe restenosis. Methods: Thirty rabbits underwent CEUS and common ultrasonography instantly, on the 3rd, 7th, 14th, 21th and 28th days after abdominal aorta was injuried by balloon. Diameter and systolic peak velocity(PSV) of the injured segment and normal segment 2cm proximal to the abnormality were measured after injury and restenosis rate was calculated. Results: ①The diameter of the lesion increased instantly after injury and decreased on the 7th day. The restenosis rate reached the peak on the 14th day, and it didn’t change afterwards. ②Light restenosis was detected by CEUS on the 7th day, earlier than common ultrasonography. Stenosis rate measured with CEUS was well related with pathology, and the correlation coefficient of it was higher than that of common ultrasonography.③CEUS displayed turbulence more clearly than color Doppler. Conclusion: CEUS could detect restenosis early and accurately. Restenosis rate measured with CEUS is more accurate than common ultrasonography and it can do great help in follow-up of restenosis.
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Received: 29 July 2008
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Corresponding Authors:
REN Wei-dong
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2008, Vol. 19 
