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| Comparison of the diagnostic value of quantitative CT pixel indices and pulmonary function test in chronic obstructive pulmonary disease |
| YE Cai-er, YE Min, WU Sui-ying, WU En-fu, CHEN Wei-jian |
| Department of Radiology, the First Affiliated Hospital of Wenzhou Medical College, Wenzhou Zhejiang 325000, China |
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Abstract Objective: To assess the diagnostic value of quantitative CT pixel indices(PI), correlated with pulmonary function test(PFT) in chronic obstructive pulmonary disease(COPD). Materials and Methods: This study included 48 patients with COPD(slight-moderate group and severe group) and 20 normal controls. All subjects underwent CT scanning of the lungs with normal respiration and PFT within one week. PI were analyzed by pulmonary quantitative software Pulmo and the parameters PI included -1024～-960, -960～-910, -910～-800, -800～-700, >-700. Analyze the correlation between PI and PFT, draw histograms of lung attenuation. Results: There was correlation between PI and PFT, there was significant correlation between PI-960～-910 and PFT. PI-960～-910 significantly increased in slight-moderate group and severe group as compared to control group, while PI-800～-700 and PI>-700 were significantly decreased(P<0.01). PI-1024～-960 and PI-910～-800 were different in three groups(P<0.05). Conclusion: PI was correlated with those data of PFT in normal respiration, which can evaluate lung function, and was combined with image element histogram to reflect the degree of COPD paitent.
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Received: 25 May 2008
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2008, Vol. 19 
