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| A comparative study of BOLD-fMRI between acute stage and early chronic stage of cerebral infarct |
| HU Tao, HUANG Sui-qiao, ZHONG Jing-lian, XIAO Fang |
| Department of Radiology, the Second Affiliated Hospital, Sun Yet-sen University, Guangzhou 510000, China |
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Abstract Objective: To investigate the cortical activation changes after stroke. Materials and Methods: BOLD-fMRI findings in 16 patients with cerebral infarction confirmed by clinical and imaging materials were analyzed. Results: The activation of patients were mainly located in the contralateral SM1 and occasionally scattered in the non-SM1 cortex. There was no statistical significance in activation volumes, activation frequencies of cortex relative to movement by longitudinal comparison between acute stage and early chronic stage. At the same time, the difference of grip strength of the two stages had no statistical significance. For better rehabilitation patients, the grip strength was becoming higher(P＜0.05), the activation volume was becoming bigger too(P＞0.05). There were three forms of changes in the contralateral SM1: became larger, became smaller and no obvious changes. Conclusions: BOLD-fMRI is a good way for developing the changes of cortical activation. Both in acute and early chronic stage, the motor areas can be activated. The contralateral SM1 is an important motor area. The change forms of SM1 were various.
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Received: 27 October 2008
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Corresponding Authors:
HUANG Sui-qiao
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2009, Vol. 20 
