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| MRI findings of ganglioglioma with correlation of clinical and pathological analysis |
| LI Feng1, JIA Chuan-hai2, ZHU Zong-ming1, ZHANG Long-jiang1, XU Yan1, ZHU Jian-guo1 |
| 1.Department of Medical Imaging, Nanjing General Hospital of Nanjing Command, Nanjing 210002, China;2.Department of Medical Imaging, Changshu No.2 People’s Hospital, Changshu Jiangsu 215500, China |
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Abstract Objective: To analyze MRI features of gangliogliomas with correlations of clinical and pathological findings. Methods: MR imaging, clinical and pathological features of gangliogliomas in 20 cases were analyzed retrospectively. Results: All cases were solitary. Eighteen lesions were supratentorial, 2 lesions were subtentorial. Amomg them, 8 lesions located in the frontal lobe, 7 lesions in temporal lobe, 1 lesion in the parietal lobe, occipital-parietal lobe, frontal-temperal lobe cerebella and medulla-cervical cord in each. Seventeen lesions were detected preoperatively MRI, 3 recurrence tumors detected postoperatively. The MR imaging appearance of gangliogliomas is variable. Gangliogliomas may be divided into solid tumors and cystic tumors on the basis of their MR characteristics. On enhanced MRI, cystic tumors may be nonenhancing or appear as a cystic lesion with an enhancing mural nodule, the focal or diffuse enhancement can be seen in the solid tumors. No or mild perilesional edema were seen for most tumors. The activation detected by EEG-fMRI was concordant with pathological focus. Conclusion: The MRI of gangliogliomas has some characteristic imaging features. It is helpful for the evaluation of gangliogliomas preoperatively combining with EEG-fMRI.
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Received: 07 May 2009
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2010, Vol. 21 
