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| Accuracy of 3.0T diffusion-weighted MRI for diagnosing the stage and grade of prostate cancer |
| ZHOU Guo-xing, CAO Kai-ming, WANG Yi-bin, ZHAO Jiang-min, HAO Nan-xin |
| Department of Radiology, East Hospital, Tongji University, Shanghai 200120, China |
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Abstract Objective: To evaluate the ability of DWI in determining the stage of prostate cancer(PCA), and to measure the correlation between apparent diffusion coefficient(ADC) with histologic grade. Materials and Methods: Forty-six patients underwent DWI with a 3.0T MR scanner using a pelvic array multi-coil. The ADC values of PCA were calculated. Results: The overall accuracy of T stage diagnosis was 80% for T2WI alone, 83% for DWI alone, 89% for T2WI plus DWI. The AZ value was significantly higher(P=0.02, 0.04) for DWI plus T2WI(AZ=0.91) than for T2WI alone(AZ=0.82) and for DWI alone(AZ=0.83). The mean ADC of G1 tumors was 1.31×103mm, 1.14×103mm for G2, 0.7×103mm for G3, The mean ADC of G3 tumors was lower than that of G1 and G2 tumors(P<0.05). Conclusion: Combined T2WI and DWI is better than DWI alone and T2WI alone in the accuracy of T stage diagnosis. The ADC value may predict the histologic grade of PCA.
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Received: 01 December 2009
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2010, Vol. 21 
