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| The diagnostic value of PET/CT in pediatric hepatoblastoma |
| The Chinese People’s Liberation Army General Hospital, Beijing 100853, China |
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Abstract Objective: To investigate the diagnostic value of 18F-FDG PET/CT in pediatric hepatoblastoma(HB). Methods: We retrospectively analyzed the PET/CT images and clinical data of 15 pediatric HB patients proved by biopsy or/and histopathology after operation, and summarized the PET/CT features of HB and the key points of its differential diagnosis. Results: Tumors showed low or mixed density with high metabolism. Calcifications were found in 8 of the 15 patients. Four patients were found with pulmonary metastases and one patient was found with both pulmonary and bone metastases by whole body PET/CT scan. Conclusion: PET/CT scan can be safely and noninvasively used in children(including infants). HB has certain characteristic findings on PET/CT, whicn is very helpful to the diagnosis and clinical staging of HB.
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Received: 26 June 2015
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[1]Dezsofi A, McLin V, Hadzic N. Hepatic neoplasms in children: A focus on differential diagnosis[J]. Clin Res Hepatol Gastroenterol, 2014, 38(4): 399-402.
[2]Meyers RL, Tiao G, de Ville de Goyet J, et al. Hepatoblastoma state of the art: Pre-treatment extent of disease, surgical resection guidelines and the role of liver transplantation[J]. Curr Opin Pediatr, 2014, 26(1): 29-36.
[3]Spector LG, Birch J. The epidemiology of hepatoblastoma[J]. Pediatr Blood Cancer, 2012, 59(5): 776-779.
[4]Fernandez-Pineda I, Cabello-Laureano R. Differential diagnosis and management of liver tumors in infants[J]. World J Hepatol, 2014, 6(7): 486-495.
[5]杨富阁，高剑波，梁盼. 儿童原发性肝细胞肝癌的CT表现及鉴别诊断[J]. 临床放射学杂志，2014，33（8）：1248-1251.
[6]McCarville MB, Roebuck DJ. Diagnosis and staging of hepatoblastoma: Imaging aspects[J]. Pediatr Blood Cancer, 2012, 59(5): 793-799. |
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2016, Vol. 27 
