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| Diagnosis and differential diagnosis of Castleman disease in children |
| 1.Department of Radiology, Qingdao Women and Children Hospital, Qingdao Shandong 266034, China; 2.Department of Radiology, Shanghai Childrens’ Medical Center, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, China |
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Abstract Objective: To analyze the imaging characteristics of ultrasound, CT and MRI and pathology of Castleman disease in children. Method: Five cases of Castleman disease proved by pathology were included in the study. Four were male and one was female, aged from 9 to 16, (11.4±2.3) years on average. The imaging characteristics of ultrasound, enhanced CT or MR were analysed. Results: Two cases were in the neck and 3 were in the abdomen. Ultrasound findings were hypoechoic nodules of internal blood flow signals or rich blood supply. CT showed low density nodules of uniform density and obvious enhancement. MR showed hypointensity on T1WI and hyperintensity on T2WI, which were homogeneously enhanced nodules with clear borders. On pathology, all cases were single-centered vascular transparent type. Conclusion: As a rare disease in children, Castleman disease can easily be misdiagnosed before operation, but better understanding can be achieved according to the specific imaging characteristics of this disease.
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Received: 09 June 2015
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2016, Vol. 27 
