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| Study on the damage degree of parotid gland uptake function in patients with xerostomia by#br# salivary gland scintigraphy |
1.Weifang Medical College, Weifang Shandong 261000, China; 2.Department of Nuclear Medicine,
the Affiliated Hospital of Weifang Medical College, Weifang Shandong 261031, China |
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Abstract Objective: To investigate the salivary gland scintigraphy(SGS) image feature of the damage degree of parotid gland in patients with xerostomia, and to comprehensively evaluate the damage degree of parotid gland uptake function combined with the 95% confidence interval. Materials and Methods: 68 patients with xerostomia and 18 healthy volunteers(control group) collected in Affiliated Hospital of Weifang Medical College from October 2013 to November 2014 were examined with 99TcmO4- salivary gland dynamic imaging. The dynamic images of parotid gland and the time-radioactive curve were observed and grouped, and the uptake rate and 95% confidence interval were calculated, then the uptake rate of the observation group and the control group were compared. Results: The UR2, UR8 and UR15 in the mild injury group, moderate injury group and severe injury group were significantly lower than those in the control group(P＜0.05). In the moderate injury group and severe injury group, the UR2, UR8 and UR15 were significantly lower than those in the mild injury group(P＜0.05). Compared with the moderate injury group, the UR8 and UR15 in the severe group were significantly decreased(P＜0.05), while the UR2 was no significant difference(P>0.05). And combined with its 95% confidence interval, UR2 1.48%~1.66% or UR8 2.05%~2.49% was diagnosed with minor injury, UR8 1.64%~2.05% or UR15 2.14%~2.64% with medium injury, UR15<2.14% with severe injury. Conclusion: The characteristic of SGS image can preliminarily evaluate the intake function of parotid gland, and parameter UR2, UR8 and UR15 can be used for quantitative analysis of the damage degree, combined with its 95% confidence interval can concisely and accurately assess the damage degree of uptake function of parotid gland in patients with xerostomia.
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Received: 18 September 2015
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2016, Vol. 27 
