超声造影联合声脉冲辐射力成像在诊断实性低回声#br# 甲状腺结节中的意义

Abstract
Figure/Table
References (12)
Related Citation (15)

Download: PDF (0 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective: To assess the value of acoustic radiation force impulse(ARFI), contrast-enhanced US(CEUS) and their combined application in differential diagnosis of solid hypo-echoic thyroid nodules． Methods: ARFI and CEUS were performed in 47 patients with 62 thyroid nodules. The results of ARFI, CEUS and their combined application, which were classified as benign or malignant ones, were compared with pathological findings. The diagnostic results of ARFI, CEUS and ARFI+CEUS were evaluated and compared． Result: The sensitivity, specificity, PPV, NPV and accuracy of the ARFI for differential diagnosis were 82.4％, 82.1％, 84.8%, 79.3%, and 82.3%, respectively. The sensitivity, specificity, PPV, NPV and accuracy of the CEUS for differential diagnosis were 88.2％, 78.6％, 83.3%, 84.6% and 83.9%, respectively. The sensitivity, specificity, PPV, NPV and accuracy of the ARFI+CEUS for differential diagnosis were 94.1%, 96.4%, 97.0%, 93.1% and 95.2%, respectively. Conclusions: ARFI and CEUS have high value in differential diagnosis of solid hypo-echoic thyroid nodules, the combined application of two methods can be helpful to improve the diagnostic accuracy．

Key words： Thyroid nodule Ultrasonography, Doppler, color

Received: 07 August 2015

PACS:	Ｒ736.1
	Ｒ581
	R445.1

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	DIAO Xue-hong
	ZHAN Jia
	CHEN Yue
	CHEN Lin
	ZHU Jun
	PANG Yun

Cite this article:

DIAO Xue-hong,ZHAN Jia,CHEN Yue, et al. Combined application of contrast-enhanced US and acoustic radiation force impulse imaging in#br# differential diagnosis of solid hypo-echoic thyroid nodules[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2016, 27(5): 333-336.

URL:

http://www.jccmi.com.cn/EN/ OR http://www.jccmi.com.cn/EN/Y2016/V27/I5/333

[1]Frates MC, Benson CB, Charboneau JW, et al. Management of thyroid nodules detected at US: Society of Radiologists in Ultrasound consensus conference statement[J]. Ultrasound Q, 2006, 22(4): 231-238.
[2]王兴田，王荣，张星荣. 声触诊组织成像鉴别甲状腺实性小结节的应用价值[J]. 中华超声影像学杂志，2013，22（2）：133-136.
[3]Ma JJ, Ding H, Xu BH, et al. Diagnostic performances of various gray-scale, color Doppler, and contrast-enhanced ultrasonography findings in predicting malignant thyroid nodules[J]. Thyroid, 2014, 24(2): 355-363.
[4]周琦，姜珏，杜晓鹏，等．超声造影在甲状腺乳头状癌中的诊断价值[J]. 中国超声医学杂志，2011，27（7）：595-597．
[5]Gul K, Ersoy R, Dirikoc A, et al. Ultrasonographic evaluation of thyroidnodules: Comparison of ultrasonographic, cytological, and histopathological findings[J]. Endocrine, 2009, 36(3): 464-472.
[6]Zhan J, Diao XH, Chai QL, et al. Comparative study of acoustic radiation force impulse imaging(ARFI) with real-time elastography(RTE) in differential diagnosis of thyroid nodules[J]. Ultrasound Med Biol, 2013, 39(12): 2217-2225.
[7]Gu J, Du LF, Bai M, et al. Preliminary study on the diagnostic value of acoustic radiation force impulse technology for differentiating between benign and malignant thyroid nodules[J]. J Ultrasound Med, 2012, 31(5): 763-771.
[8]Xu JM, Xu HX, Xu XH, et al. Solid hypo-echoic thyroid nodules on ultrasound: the diagnostic value of acoustic radiation force impulse elastography[J]. Ultrasound Med Biol, 2014, 40(9): 2020-2030.
[9]陈立斌，蒋天安，王菁，等. 超声造影及定量分析技术鉴别甲状腺实性肿块良恶性的价值[J]. 中华超声影像学杂志，2012，21（12）：1035-1039.
[10]Zhang B, Jiang YX, Liu JB, et al. Utility of contrast enhanced ultrasound for evaluation of thyroid nodules[J]. Thyroid, 2010, 20(1): 51-57.
[11]Nemec U, Nemec SF, Novotny C, et al. Quantitative evaluation of contrast-enhanced ultrasound after intravenous administration of a microbubble contrast agent for differentiation of benign and malignant thyroid nodules: assessment of diagnostic accuracy[J]. Eur Radiol, 2012, 22(6): 1357-1365.
[12]Hornung M, Jung EM, Georgieva M, et al. Detection of microvascularization of thyroid carcinomas using linear high resolution contrast-enhanced ultrasonography(CEUS). Clin Hemorheol Microcirc, 2012, 52(2-4): 197-203.