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| CT and MRI in the diagnosis of von Hippel-Lindau syndrome and the literature review(with 2 cases report) |
| GAO Mei-mei, YE Jian-jun, CHENG Man-ping, NIU Juan-qin |
| Department of Medical Image Center, Lanzhou General Hospital, Lanzhou 730050, China |
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Abstract Objective: To explore the clinical and imaging characteristics of von Hippel-Lindau syndrome(VHL), to improve the understanding of the disease in order to avoid misdiagnosis or missed diagnosis. Methods: The clinical and imaging data of 2 cases of VHL syndrome diagnosed by CT and MRI were analyzed retrospectively, and the related literatures were reviewed, and then the basis of imaging diagnosis was summed up. Results: There were 2 cases of central nervous system hemangioblastoma. One case with kidney cancer and polycystic pancreas, the other case with bilateral adrenal pheochromocytoma. Conclusion: Before the gene final diagnosis, the comprehensive inspections of CT and MRI are the major means of diagnosis of VHL syndrome. MRI has the advantage in the diagnosis of hemangioblastoma of central nervous system.
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Received: 01 February 2016
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