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The value of CT sign “thyroid marginal contact” of papillary thyroid carcinoma to#br#
predict the cervical lymph node metastasis |
YIN Bing-xin1, LI Ning2, HAN Zhi-jiang3 |
1. Department of Radiology, Hangzhou Hospital of Traditional Chinese Medicine, Hangzhou 310007, China;
2. Department of Radiology, Fuyang People’s Hospital, Hangzhou 311400, China; 3. Department of Radiology,
Hangzhou First People’s Hospital, Hangzhou Center for Diagnosis and Treatment of Thyroid Disease, Hangzhou 311200, China |
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Abstract Objective: To investigate the value of using CT sign “thyroid marginal contact” of papillary thyroid carcinoma(PTC) to predict the central lymph node metastasis(CLNM). Methods: This article reviewed 207 patients with surgically and pathologically verified PTC, among the patients, 104 patients with CLNM, and 103 patients without CLNM. According to the area of thyroid marginal contact, divided the patients into three groups: <1/4 group, 1/4~<1/2 group and ≥1/2 group. The data was analyzed by Chi-square test, and the sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of <1/4 group, 1/4~<1/2 group,≥1/2 group and 1/4~<1/2 group combined with ≥1/2 group(≥1/4 group) in positive CLNM were calculated. Results: The Chi-square test among multiple groups indicated that there were statistical differences between three groups in CLNM(χ2=14.540, P<0.05). Pairwise comparison with Chi-square test indicated that there was statistical difference between <1/4 group and 1/4~<1/2 group(χ2=9.514, P<0.012 5), <1/4 group and ≥1/2 group(χ2=13.715, P<0.012 5), and there was no statistical difference between 1/4~<1/2 group and ≥1/2 group(χ2=0.752, P>0.012 5). The sensitivity(88%) and the accuracy(61%) of ≥1/4 group were the highest; the specificity of the ≥1/2 group is the highest(72%). Conclusion: The thyroid marginal contact can provide important evidence for the dissection of CLNM. The sensitivity and the accuracy of ≥1/4 group are the highest.
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Received: 20 July 2016
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