IVIM理论中各参数值在甲状腺良恶性结节方面的鉴别诊断价值

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Abstract Objective: To study the value of each parameter in IVIM theory in the differential diagnosis of benign and malignant thyroid nodules. Methods: Totally 25 patients with thyroid nodules undergoing surgery(31 nodules) and a normal control group of 10 samples underwent GE 3.0T routine MRI scan and multiple b value diffusion weighted scan(b=0, 10, 20, 50, 100, 200, 400, 800, 1 200 mm2/s) before operation, D value, D* value and F value in the theory of IVIM of the patients and members in normal control group were measured. ROC curve was drawn, the parameters were compared in the differential diagnosis of benign and malignant thyroid nodules. Results: Eighteen of 31 thyroid nodules were benign nodules with nodular goiter in 12 cases and adenoma in 6 cases, and 13 were thyroid papillary carcinoma which had been pathologically confirmed. D values were statistically significant differences between each other, among the three groups, namely normal control group, benign nodule group and papillary carcinoma group. F values were no significant differences. D* values were significant differences between benign nodule group and normal control group. D* values were also significant differences between normal control group and papillary carcinoma group. D* values were no significant differences between benign nodule group and papillary carcinoma group(P>0.05). Taken D=1.68×10-3 mm2/s as threshold for diagnosing benign and malignant nodules, sensitivity was 77.8%, specificity was 90.9%. Conclusion: D value in IVIM theory has important value for the differential diagnosis of benign and malignant thyroid nodules.

Key words： Thyroid nodule Magnetic resonance imaging

Received: 27 May 2016

PACS:	Ｒ581
	Ｒ445.2

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	SU Yu
	GAO Si-jia
	CAO Ji-bin
	XIE Ming-fei

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SU Yu,GAO Si-jia,CAO Ji-bin, et al. ach parameter value in differential diagnosis of benign and malignant thyroid nodules under#br# IVIM theoretical aspects[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2017, 28(3): 176-179.

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http://www.jccmi.com.cn/EN/ OR http://www.jccmi.com.cn/EN/Y2017/V28/I3/176

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