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| Preoperative US features of papillary thyroid microcarcinoma predict central compartment lymph node metastases |
| WANG Ying1, DING Jin-wang2, MA Chen-xia2, HAN Zhi-jiang2, ZHANG Wo2,
DAI Chao-chao2, LOU Jun3, LEI Zhi-kai2, PENG You2, LIU Ling-yan1 |
| 1. Department of Ultrasonography, Songyang People’s Hospital, Songyang Zhejiang 323400, China;
2. Nanjing Medical University Affiliated Hangzhou Hospital(Hangzhou First People’s Hospital), Hangzhou 310006, China;
3. Department of Ultrasonography, Hangzhou Cancer Hospital, Hangzhou 310002, China |
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Abstract Objective: To evaluate the clinical significance of preoperative US features of papillary thyroid microcarcinoma(PTMC) predicting central compartment lymph node metastases(CCLNM). Methods: The sonographic features of 182 patients with pathologically confirmed PTMC in Hangzhou First People’s Hospital from March 2014 to October 2015 were retrospectively reviewed. The relationship between ultrasound characteristics of PTMC and CCLNM was analyzed by univariate analysis and logistic regression analysis. Results: The ipsilateral central lymph nodes from 220 sides were dissected in 182 cases of PTMC, of which 88 side of central lymph nodes were metastasis, so the rate of lymph node metastasis was 40%. Univariate analysis revealed that CCLNM was associated with certain preoperative US features, which included lesion location, tumor size, capsule invasion and microcalcification. Moreover, Logistic regression analysis only showed that the preoperative US features of lesion location, tumor size and capsule invasion were independent factors correlated with CCLNM. Conclusions: The lesion location, tumor size and capsule invasion determined by preoperative ultrasound in PTMC are positively correlated with CCLNM.
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Received: 20 January 2017
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