双能量CT评估喉癌喉软骨侵犯的临床价值

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Abstract Objective: To explore the evaluation feasibility of laryngeal cartilage invasion in laryngeal carcinoma. Methods: Sixty cases with confirmed of laryngeal carcinoma were performed on dual energy CT, including 28 cases with unilateral laryngeal cartilage invasion and 32 cases without laryngeal cartilage invasion proved by operation and pathology were analyzed retrospectively. Evaluation of iodine overlay images and conventional enhanced images laryngeal cartilage invasion signs(laryngeal cartilage sclerosis, lysis, erosion and exralaryngeal tumor spread) sensitivity and specificity; Arterial and venous phase, invaded cartilage tumor and normal cartilage CT value and spectrum curve slope and iodine concentration were measured and compared. Arterial and venous phase, invaded cartilage tumor and normal cartilage CT value and spectrum curve slope and iodine concentration were measured and compared. Results: Iodine overlay images judging lysis of laryngeal cartilage the sensitivity was 92.3%, the specificity was 86.7%, the sensitivity of erosion was 82.4% and the specificity was 81.8%, which was higher than that of conventional CT images(P<0.05), judgment of laryngeal cartilage sclerosis, exralaryngeal tumor spread had no difference(P>0.05). Tumor, invaded cartilage, normal cartilage at different time CT values were different(P<0.05), but AUC were<0.5. In the arteries and venous phase, there were differences in the spectral curve, slope and iodine concentration of the tumor, invaded cartilage and normal cartilage(P<0.05), and the concentration of iodine in tumor was higher than that in invaded cartilage and normal cartilage. The slope of the spectral curve, AUC in arterial phase was 0.970, sensitivity was 88.9%, specificity was 100%. The venous phase AUC was 0.944, the sensitivity was 81.5%, and the specificity was 96.3%. Arterial phase iodine concentration was AUC was 0.995, sensitivity was 92.6%, specificity was 100%, venous phase was AUC was 0.905, sensitivity was 77.8%, specificity was 88.9%. Conclusion: Dual energy CT dual energy iodine imaging and the concentration of iodine, the slope of the energy spectrum curve in the dynamic and venous phase are of some value in judging laryngeal cartilage invasion.

Key words： Laryngeal neoplasms Laryngeal cartilages Tomography, X-ray computed

Received: 20 April 2017

PACS:	Ｒ739.65
	Ｒ814.42

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	Articles by authors
	LI Shu-juan
	HAN Dan
	LU Ren-cai
	JIANG Jie
	ZHANG Xia
	SHEN Sha-sha
	ZHAO Wei

Cite this article:

LI Shu-juan,HAN Dan,LU Ren-cai, et al. The clinical value of dual-energy CT at evaluation of laryngeal cartilage invasion in laryngeal carcinoma[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2018, 29(2): 87-91.

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http://www.jccmi.com.cn/EN/ OR http://www.jccmi.com.cn/EN/Y2018/V29/I2/87

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