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MRI features of malignant peripheral nerve sheath tumor |
WANG Qian, REN Cui-ping, WANG Shan, LI Fei, SUN Nan, CHENG Jing-liang |
Department of MRI, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China |
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Abstract Objective: To explore the typical and common MRI features of malignant peripheral nerve sheath tumor(MPNST) in order to improve the preoperative diagnostic accuracy. Methods: A total of 26 patients MRI with MPNST confirmed by pathology were analyzed retrospectively(n=26, 20 patients underwent enhanced scan). Results: ①Typical features: atypical“target sign”(n=12), 9 cases in the limbs, 2 cases in lumbar spinal canal, 1 case in the soft tissues around the hip joint; “entering or exiting nerve sign”(n=6), all were located in the region of the sciatic nerve; “fascicular sign”(n=6), all were located in the limbs. ②Dynamic enhancement modes: 8 lesions(40%) showed type Ⅱ, 10 lesions(50%) showed type Ⅰ, the solid parts showed annular or patchy or nodular inhomogeneous enhancement; 2 lesions(10%) showed type Ⅲ enhancement, the solid parts showed homogeneous enhancement.③Common features: 2 cases showed irregular shape, rough edge, 14 cases showed regular shape, smooth edge; Five cases did not infiltrate to the soft tissue, 21 cases were infiltrative; Twenty-two cases(84.6%) T1WI showed equal or low signal, 25 cases(96.2%) T2WI showed equal ormixed high signal. Conclusion: There were typical MRI features in most of the MPNST, the special signs such as atypical “target sign”, “entering or exiting nerve sign”, “fascicular sign”, the type Ⅰ, type Ⅱ dynamic enhancemant modes have helpful to make the diagnosis.
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Received: 10 April 2017
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