临床前期阿尔茨海默病的功能MRI研究进展

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Abstract Alzheimer’s disease(AD) is considered as a continuously pathophysiological process. Special pathological changes of AD has occurred decades prior to the onset of clinical symptoms. Currently, due to the advanced neuroimaging techniques and biochemical tests, variant AD-related biomarkers are gradually identified, making it possible to diagnose AD in the preclinical stage and further intervene the process of the disease. Functional MRI(fMRI), which is helpful to reveal the early brain functional activities in preclinical AD, is the most common form of functional imaging techniques. This review is about researches involving preclinical AD based on fMRI in recent years.

Key words： Alzheimer disease Magnetic resonance imaging

Received: 27 June 2017

PACS:	Ｒ742
	Ｒ445.2

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	Articles by authors
	SHENG Can1
	LIU Fang1
	HAN Ying2

Cite this article:

SHENG Can1,LIU Fang1,HAN Ying2. Progress of research on preclinical Alzheimer’s disease based on functional MRI[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2018, 29(5): 359-362.

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http://www.jccmi.com.cn/EN/ OR http://www.jccmi.com.cn/EN/Y2018/V29/I5/359

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