分子功能影像在头颈部副神经节瘤的临床应用

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Abstract Paragangliomas of head and neck are usually slow-growing tumors that are benign in most cases. Metastasis may also occur. Paragangliomas in head and neck usually do not produce catecholamines and related substances. They almost all have succinate dehydrogenase gene germline mutations and overexpression of somatostatin receptor. Conventional anatomical imaging has low sensitivity and specificity for detecting head and neck paragangliomas. Molecular imaging is gradually used in clinical diagnosis, which can significantly improve the sensitivity and specificity of the diagnosis of head and neck paragangliomas. Molecular imaging is useful for detection and characterization of head and neck paragangliomas and to demonstrate synchronous paragangliomas at other sites and distant metastases, which is critical because it can significantly affect treatment plan of patients.

Key words： Head and neck neoplasms Paraganglioma Positron-emission tomography Tomography, X-ray computed

Received: 19 July 2017

PACS:	Ｒ739.91
	Ｒ730.264
	Ｒ817.4
	Ｒ814.42

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	HU Yue
	MA Xiu-lan

Cite this article:

HU Yue,MA Xiu-lan. Application of molecular imaging in paraganglioma of head and neck[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2018, 29(6): 439-442.

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http://www.jccmi.com.cn/EN/ OR http://www.jccmi.com.cn/EN/Y2018/V29/I6/439

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