注意缺陷多动障碍执行功能缺陷：基于Stroop效应的fMRI研究

doi:DOI:10.12117/jccmi.2018.08.007

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Abstract Objective: The study investigated the defects of executive function in attention deficit and hyperaction disorder(ADHD) children when they were performing Stroop color-word tasks, by functional magnetic resonance imaging(fMRI). Methods: Thirteen ADHDs and thirteen healthy controls were enrolled. The behavioral data and functional magnetic resonance images were required when the participants were performing a series of Stroop color-word tasks, in which he high conflict, low adjusted conditions and high adjusted, low conflict conditions were created by setting the ratio of congruent and incongruent trials in a block. The voxel-wise t-tests were applied to analyze the group differences of tasks, and quantified the brain response related to response time to analyze the efficiency in execution, to analyze the defects of executive function in ADHD. Results: The behavioral data showed that the adjustment, and congruence effects were significant(P<0.000 1), except the group effects(P>0.05). However, the interaction between group, adjustment and congruence were significant(P<0.02, P<0.000 1, P<0.001). The image analyses detected a cluster of right lateral prefrontal cortex(-36, 42, 33) and a cluster of anterior cingulate cortex(0, 52, 9) with lower efficiency in ADHD patients than that in healthy controls during incongruent tasks in high adjustment and conflict conditions, respectively. Conclusion: The results agree that the ADHD may arouse regions or higher activation or decrease them. The areas of lateral prefrontal cortex and anterior cingulate cortex to perform executive tasks, due to the lower efficiency in the brain areas including anterior cingulate cortex and lateral prefrontal cortex, which are related to conflict response and executive control.

Key words： Attention deficit disorder with hyperactivity Magnetic resonance imaging

Received: 31 May 2018

PACS:	Ｒ749.94
	Ｒ445.2

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	LIU Jia-cheng1
	CHU Xing2
	XING Jiong2

Cite this article:

LIU Jia-cheng1,CHU Xing2,XING Jiong2. The defects of executive function in attentional deficit and hyperaction disorder: a study of Stroop effects by fMRI[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2018, 29(8): 556-559.

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http://www.jccmi.com.cn/EN/DOI:10.12117/jccmi.2018.08.007 OR http://www.jccmi.com.cn/EN/Y2018/V29/I8/556

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