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| CT findings of Treacher Collins syndrome in infants |
| LIANG Qiong-he, GUAN Hong-mei, HAN Su-fang, YANG Ming |
| Department of Radiology, Children’s Hospital of Nanjing Medical University, Nanjing 210008, China |
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Abstract Objective: To improve the understanding of Treacher Collins syndrome(TCS) in infants from the perspective of imaging. Methods: Twenty-one cases of TCS in infants, 13 males and 8 females, aged fom 13 days to 3 years and 5 months. A retrospective analysis and summary of the plain and reconstructed images of CT was performed. Classification of mandibular retraction was made. Results: Zygomatic hypoplasia in 21 cases, mandibular hypoplasia in 21 cases, 18 cases of cleft palate, tongue retropulsion in 11 cases, 20 cases of abnormal external ear, 17 cases of abnormal external auditory canal, 21 cases showed abnormal ossicles, and mastoid air cells sclerosis in 21 cases. There were 7 cases of mandibular retraction type Ⅰ, 6 cases of type Ⅱ, 5 cases of type Ⅲ, and 3 cases of type Ⅳ. Conclusion: The CT performance of TCS has certain characteristics, dysostosis of facial bone mainly occurs in zygomatic bone, involving the temporal bone, mandible and maxilla, combined with cleft palate, external ear and middle ear malformation at the same time. The management of mandibular retraction in infants is related to the prognosis of TCS. The mandibular retraction angle could be measured on CT median sagittal MPR image, which is used to guide the clinical operation.
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Received: 20 December 2017
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