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Differential diagnosis between giant cell tumor and solitary plasmacytoma of the spine |
LI Feng, CUI Jiu-fa, FENG Shuo, FENG Wei-hua |
Affiliated Hospital of Qingdao University, Qingdao Shandong 266003, China |
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Abstract Objective: To investigate the imaging features of spine giant cell tumor(GCT) and solitary plasmacytoma of bone(SPB), so as to improve the understanding of the two kinds of tumors. Methods: The CT and MRI findings of 19 cases of GCT and 12 cases of SPB confirmed by pathology were compared and analyzed, and the differences of imaging findings were summarized. Results: In 19 cases of GCT, 68.4% were aged between 20 and 40, 11 cases were located in the sacral vertebra, 5 in the thoracic vertebra, 2 in lumbar vertebra and 1 in cervical vertebra. Thirteen cases were swelling and osteolytic bone destruction, 6 cases of compression fractures with severe compression, the residual bone crest slender and 68.75% of the soft tissue masses occurred around the centrum. Because of easy occurrence of bleeding and necrosis, MRI signals were often uneven. In 12 cases of SPB, 58% were aged between 40 and 60, 10 cases occurred in the thoracic vertebra, 1 in cervical vertebra and 1 in lumbar vertebra. Ten cases were osteolytic bone destruction, 7 cases of mild and moderate compression in 10 cases of compression fracture, the residual bone crest was relatively thick. 83.33% of the soft tissue masses were located in the spinal canal, and MRI signals were often homogeneous due to rare cystic degeneration and bleeding. Conclusion: The bone destruction form, the degree of compression fracture, the location of soft tissue masses, the shape of residual bone crest and cystic degeneration and bleeding signal are helpful for the differential diagnosis of GCT and SPB.
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Received: 27 November 2017
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