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| The clinical value of ultrasound for diagnosis of pediatric neuroblastoma |
| ZHANG Yao, WANG Shuo, LIU Bo-wei |
| Department of Ultrasound, Shengjing Hospital, China Medical University, Shenyang 110004, China |
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Abstract Objective: To explore the clinical value of ultrasound for diagnosis of pediatric neuroblastoma(NB). Methods: A retrospective review of 37 cases of pediatric NB with ultrasound examination and pathologic verification from January 2008 to March 2017 was conducted. Results: Among the 37 cases, 13 cases(35.1%) were stage Ⅰ. 6(16.2%) were stage Ⅱ. 8 were stage Ⅲ(21.6%). 7(18.9%) were stage Ⅳ, and 3(8.1%) were stage Ⅳ-s. The primary tumor was located in adrenal(n=27, 73%, 18 cases in left adrenal and 9 in right adrenal), retroperitoneal sympathetic nerve(n=6, 16.2%), pelvic cavity(n=4, 10.8%), and neck(n=1, 2.7%), respectively. The ultrasonographic features were as follows: 29 inhomogeneous hypoechoic solid tumors, 7 cystic and solid tumors, 1 cystic tumor, and 17 cases showing intratumoral calcification. The range of tumors was as below: limited to local(n=10), crossing the middle line of the body(n=9), invasion of adjacent tissues and organs(n=13), retroperitoneal vessels involved(n=14), liver metastasis(n=7), and bone metastasis(n=3), respectively. The accurate rate of diagnosis by ultrasound was 91.9%(34/37). Conclusions: Ultrasound can be used as a feasible and effective method to diagnose and follow up the pediatric NB.
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Received: 16 May 2018
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2019, Vol. 30 
