心肌运动定量分析技术在评价多囊卵巢综合征合并胰岛素抵抗患者左室收缩功能中的应用价值

doi:DOI:10.12117/jccmi.2018.12.006

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Abstract Objective: To investigate the clinical value of cardiac motion quantification(CMQ) technique in evaluating left ventricular systolic function in patients with polycystic ovary syndrome complicated with insulin resistance(PCOS-IR). Methods: Fifty-five patients with polycystic ovary combined with insulin resistance were selected as PCOS-IR group and 55 healthy volunteers were selected as control group. The CMQ technique was used to measure the subendocardial, epicardial and global longitudinal strain(Ls), radial strain(Rs) and circumferential strain(Cs) of systolic myocardium, and the difference of cross wall was calculated. At the same time, the rotation angle and torsional angle of the left ventricular short axis were measured, and the peak value of rotation angle gradient of cross wall and the peak value of torsional angle gradient of cross wall were calculated. The difference of all the parameters between the two groups was compared. Results: ①Left ventricular systolic Ls: From the basal to apical segments, it showed an increasing trend. The peak strain of the subendocardial myocardium at the same level was greater than that under the epicardial(P<0.05). The Ls and difference of cross wall in the PCOS-IR group were lower than those in the control group(P<0.05). ②Left ventricular short axis Rs: The level of papillary muscle was the largest, the mitral valve was the second, and the apical level was the smallest. And there was no statistical significance between the two groups(P<0.05). ③Left ventricular short axis Cs: Increasing from mitral valve level to apical level, the peak strain of the subendocardial myocardium at the same level was greater than that under the epicardial(P<0.05). Left ventricular systolic Cs and difference of cross wall in the PCOS-IR group were lower than those in the control group(P<0.05). ④Myocardial rotation and torsion angle: Those of subendocardium were higher than those of epicardial myocardium at the same level in the two groups(P<0.05). The rotation angles at the apical level, the rotation angles of left ventricular short axis mitral valve epicardium, and the torsional angles of the left ventricle in the PCOS-IR group were higher than those in the control group(P<0.05). The peak value of rotation angle gradient of cross wall and the peak value of torsional angle gradient of cross wall of left ventricular apical level in the control group were higher than those in the PCOS-IR group(P<0.05). The subendocardial rotation angle and the whole rotation angle of mitral valve in the PCOS-IR group were higher than those in the control group, and the angle gradient of transmural rotation in PCOS-IR group was lower than that of control group(P<0.05). Conclusion: CMQ technique can accurately detect the changes of left ventricular systolic function in patients with PCOS-IR, and can provide a new diagnostic basis for evaluating the early changes of myocardial systolic function in patients with PCOS-IR.

Key words： Polycystic ovary syndrome Insulin resistance Ventricular function, left Ultrasonography

Received: 15 May 2018

PACS:	Ｒ711.75
	Ｒ587.1
	Ｒ445.1

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	Articles by authors
	DU Qi-gen
	MI Xiang-qin
	XU Hong-wei
	SHANG Wei-min
	ZHOU Li-ping
	CHEN Wei

Cite this article:

DU Qi-gen,MI Xiang-qin,XU Hong-wei, et al. Evaluation of left ventricular systolic function in patients with polycystic ovary and insulin resistance by cardiac motion quantification[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2018, 29(12): 860-865.

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http://www.jccmi.com.cn/EN/DOI:10.12117/jccmi.2018.12.006 OR http://www.jccmi.com.cn/EN/Y2018/V29/I12/860

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