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| Study on the relationship between spontaneous echo contrast in the internal jugular vein and stroke |
| CHEN Wei-nan, ZHANG Chun-mei, ZHANG Juan |
| Department of Ultrasound, the First Affiliated Hospital of Harbin Medical University, Harbin 150001, China |
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Abstract Objective: To investigate the correlation between internal jugular vein spontaneous echo contrast(IJVSEC) and stroke. Methods: One hundred patients with ischemic stroke were selected as stroke group and 50 normal persons without stroke history were selected as control group. All subjects underwent routine ultrasound examination and stroke risk factor analysis. Then, the severity of stroke was evaluated by National Institute of Health Stroke Scale(NIHSS). According to the trial of org 10 172 in acute stroke treatment(TOAST), stroke patients were divided into five subtypes. The relationship between different etiological types and related risk factors, laboratory indicators and ultrasound detection indicators was analyzed, and all data were analyzed statistically. Results: The fibrinogen, hemoglobin, D2 polymers, intimal-medial thickness(IMT), NIHSS score, plaque integral and spontaneous echo contrast(SEC) score in stroke group were significantly higher than those in control group(P<0.001), but there was no significant difference between the two groups in MV of bilateral internal jugular vein(P>0.05). Plaque integral and IMT were different in different subtypes of stroke patients. There was no significant difference in SEC score and MV of bilateral internal jugular vein between atherosclerotic stroke group and other stroke types group(P>0.05). SEC score was positively correlated with fibrinogen, hemoglobin, D2 polymers, NIHSS score(r=0.274, P<0.001; r=0.330, P<0.001; r=0.421, P<0.001; r=0.731, P<0.001), not correlated with plaque integral and IMT(r=0.049, P=0.547; r=0.025, P=0.759), and SEC score was positively correlated with jugular venous reflux(JVR)(r=0.409, P＜0.001). Conclusions: IJVSEC is more likely to occur in patients with ischemic stroke, and there is a close correlation between the two, and the severity of IJVSEC is correlated with the severity of stroke. IJVSEC phenomena in stroke patients may be formed through other mechanisms besides atherosclerosis, and whether IJVSEC can be used as a marker or therapeutic index of stroke needs further study.
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Received: 08 May 2018
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