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| The value of 1.5T MR apparent diffusion coefficient ratio in the diagnosis of tongue cancer |
| ZHENG Xue-wei1, DING Jun1, LIU Shuo1, GUAN Yu-yao1, LI Tong1, FENG Yan2, FU Wei-guang2, YU Bao-ting1 |
| 1. Department of Radiology, China-Japan Union Hospital of Jilin University, Changchun 130033, China;
2. Department of Radiology, Jilin Provincial People’s Hospital, Changchun 130021, China |
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Abstract Objective: To evaluate the value and correlation of the ratio of apparent diffusion coefficient(ADC) of tongue lesions and surrounding normal glands in the diagnosis, pathological grading and staging of tongue cancer. Methods: Sixty patients with tongue lesions confirmed by surgical pathology in China-Japan Union Hospital of Jilin University from March 2017 to March 2019 were collected. Routine MRI and DWI scanning were performed before operation, and the ADC values of lesions and surrounding glands were measured and the ADC ratio was calculated. Results: ①There were 40 cases of tongue cancer and 20 cases of tongue benign lesions. The ADC ratio of tongue cancer was -0.13±0.17 and that of tongue benign lesions was 0.09±0.10, and the difference between the two ratios was statistically significant(t=5.129, P<0.05). ②The ADC ratio of the highly differentiated group was 0.02±0.07, the ADC ratio of the moderately differentiated group was -0.14±0.17, and the ADC ratio of the low-differentiated group was -0.26±0.09. There were statistically significant differences among the three groups(F=3.593, P=0.047). ③The ADC ratio of the advanced tongue cancer group(T3+T4) was -0.20±0.13, which was lower than that of the early tongue cancer group(Tis+T1+T2), the ADC ratio of the early tongue cancer group was 0.00±0.17(t=3.314, P=0.03<0.05). The difference between T4 and T1 and T2 was statistically significant(P<0.05), while no significant difference was found in other pairwise comparisons(P>0.05). Conclusion: The apparent diffusion coefficient ratio can provide reference for the differential diagnosis of benign and malignant tongue lesions and the pathological classification and staging of tongue cancer, and has important clinical significance.
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Received: 22 July 2019
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