Effect of hemodialysis on blood lipid metabolism and carotid ultrasound in elderly patients
LI Xiang1, YANG Qing2, XU Yan1
1. Department of Ultrasound, Affiliated Hospital of Qingdao University, Qingdao Shandong 266003, China;
2. Qilu Hospital of Shandong University(Qingdao), Qingdao Shandong 266035, China
Abstract Objective: To analyze the effect of hemodialysis on carotid ultrasound and lipid metabolism in elderly patients. Methods: One hundred and fifty elderly hemodialysis patients and 120 normal subjects were selected as the elderly hemodialysis group(age 60~83) and the control group(age 60~85). Cholestero(TC), triglyceride(TG), high-density lipoprotein(HDL-C), low-density lipoprotein(LDL-C), apolipoprotein A1(apoA1), apolipoprotein B(apoB) and fibrinogen(FIB) were measured. All subjects underwent bilateral carotid color Doppler Ultrasonic examination. Results: The levels of TC, TG, LDL-C and apoB in the elderly hemodialysis group were significantly higher than those in the control group(P<0.05). The FIB in the elderly hemodialysis group was significantly higher than that in the control group(P<0.01). There were significant differences in the carotid intima-media thickening, plaque detection rate and artery stenosis rate between the elderly hemodialysis group and the control group(P<0.01). Conclusion: Hemodialysis can affect the metabolism of blood lipid and the change of carotid ultrasound in elderly patients, mainly make the vascular endothelial dysfunction, accelerate the process of carotid atherosclerosis. Carotid ultrasound can reflect the degree of vascular disease in elderly hemodialysis patients, and provide some basis for treatment and prevention.
LI Xiang1,YANG Qing2,XU Yan1. Effect of hemodialysis on blood lipid metabolism and carotid ultrasound in elderly patients[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2020, 31(4): 248-251.
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