JOURNAL OF CHINA MEDICAL IMAGING
Current Issue | Archive | Adv Search |
Clinical application of 18F-FDG PET/CT in extramammary Paget’s disease
LIU Wei-kun, ZHOU Xuan, PENG Li, WANG Peng-long, DUAN Yu-jiao, CHENG Lei, YIN Ji-lin
Gosun Medical Imaging Diagnostic Center, Guangzhou 510017, China
Download: PDF (0 KB)   HTML (1 KB) 
Export: BibTeX | EndNote (RIS)      
Abstract  Objective: To investigate the role of 18F-FDG PET/CT in the diagnosis, staging and follow-up of extramammary Paget’s disease(EMPD). Methods: Whole-body 18F-FDG PET/CT images of 13 patients with newly diagnosed or suspected recurrent EMPD were retrospectively analyzed. The lesions with increased uptake of 18F-FDG were positive and were measured with maximum standard uptake(SUVmax). Results: Among the 13 patients with EMPD, 11 received 18F-FDG PET/CT before surgery and 2 received 18F-FDG PET/CT after surgery. Eleven patients had skin lesions, 18F-FDG uptake of all skin lesions was increased in varying degrees, SUVmax ranged from 1.4 to 15.9. The skin lesions thickness was more than or equal to 1 cm in 4 cases(4/11), and SUVmax ranged from 4.6 to 15.9, the thickness was less than 1 cm in 7 cases(7/11), and SUVmax ranged from 1.4 to 3.9. The SUVmax of skin lesions between two groups was compared by independent sample t-test and the results showed that t=2.821, P=0.064, without statistical significance. Lymph node metastasis was found in 7(7/13), and SUVmax ranged from 3.4 to 15.1, and one of them(1/7) was suspected recurrence after EMPD surgery and radiotherapy. In 13 EMPD patients, distant metastasis was found in 2 cases(1 case with single bony metastasis, 1 case with multiple lung, liver and bone metastases), all lesions showed increased FDG uptake in varying degrees and SUVmax ranged from 3.8 to 14.0. Two cases(2/13) of EMPD with lung cancer or colon cancer were found. Conclusion: 18F-FDG PET/CT diagnosis of EMPD mainly depends on the thickness of the lesion, which is more sensitive to the diagnosis of metastasis. Therefore, 18F-FDG PET/CT is very useful for the diagnosis, staging and follow-up of EMPD.
Key wordsSkin neoplasms      Fluorodeoxyglucose F18      Positron-emission tomography     
Received: 07 January 2020     
PACS:  R739.5  
  R817.4  
Service
E-mail this article
Add to my bookshelf
Add to citation manager
E-mail Alert
RSS
Articles by authors
LIU Wei-kun
ZHOU Xuan
PENG Li
WANG Peng-long
DUAN Yu-jiao
CHENG Lei
YIN Ji-lin
Cite this article:   
LIU Wei-kun,ZHOU Xuan,PENG Li, et al. Clinical application of 18F-FDG PET/CT in extramammary Paget’s disease[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2020, 31(8): 588-591.
URL:  
http://www.jccmi.com.cn/EN/10.12117/jccmi.2020.08.015     OR     http://www.jccmi.com.cn/EN/Y2020/V31/I8/588
Copyright © Editorial Board of JOURNAL OF CHINA MEDICAL IMAGING
Supported by:Beijing Magtech