实时剪切波弹性成像联合超声评分在原发性干燥综合征
腮腺受损诊断中的价值

doi:10.12117/jccmi.2019.11.004

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Abstract Objective: To explore the diagnostic value of Young’s modulus by real-time shear wave elastography(RT-SWE) combined with sonographic score in parotid gland with primary Sjogren’s syndrome(pSS). Methods: One hundred and forty suspected Sjogren’s syndrome patients were enrolled in this study. The bilateral parotid gland was examined by ultrasonography and RT-SWE. Semiquantitative scores and the Young’s modulus were obtained. The differences of sonographic scores and Young’s modulus between two sides of parotid glands in pSS group and the non-pSS group were analyzed. And the diagnostic efficacy of sonographic scores combined with Emean in parotid gland damage of pSS was also analyzed, the ROC curve was plotted. Results: ①Sonographic score in pSS group was higher than non-pSS group(P<0.001). The ROC curve showed that the best cut-off value was 2, the sensitivity and specificity was 81.6% and 93.7%, respectively, and the area under the curve(AUC) was 0.906. ②The Young’s modulus between two sides of parotid glands in pSS group or non-pSS group showed no significant difference(P>0.05). The difference of Young’s modulus between the two groups was statistically significant(P<0.001). The ROC curve showed that the optimal cut-off value of Emean was 9.9 kPa, the sensitivity and specificity was 75.0% and 95.3%, respectively, and the AUC was 0.876. ③The sensitivity and specificity of parotid ultrasonography scores combined with RT-SWE for diagnosis of pSS was 88.2% and 90.6%, respectively, and the AUC was 0.950. The AUC of the combined score was greater than the AUC of the sonographic scores or Young’s modulus(P value was 0.033 and 0.001, respectively). Conclusion: The parotid sonographic scores can provide a semi-quantitative index for the uniformity of glandular echo. RT-SWE can measure the hardness of parotid gland. The combination of these two is highly accurate in the evaluation of parotid gland with pSS, which is worthy of clinical promotion.

Key words： Sjogren’s syndrome Parotid gland Ultrasonography

Received: 04 December 2018

PACS:	Ｒ781.7
	Ｒ445.1

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	Articles by authors
	WANG Jiao-jiao
	ZHANG Lei
	LIU Sheng-yun
	MA Xiao
	QI Qing-hua
	DONG Gang

Cite this article:

WANG Jiao-jiao,ZHANG Lei,LIU Sheng-yun, et al. The diagnosis value of RT-SWE combined with sonographic score in parotid gland damage of primary Sjogren’s syndrome[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2019, 30(11): 773-777.

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http://www.jccmi.com.cn/EN/10.12117/jccmi.2019.11.004 OR http://www.jccmi.com.cn/EN/Y2019/V30/I11/773

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