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Clinic value of ultrasonogram in exploring fetal ductus arteriosus aneurysm on the third trimester of pregnancy |
KOU Hong-ju, HE Hui-liao, WANG Liang, LI Xiu-yun, XIAO Li-li |
Department of Utrasonography, the Second Affiliated Hospital of Wenzhou Medical University,
Wenzhou Zhejiang 325027, China |
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Abstract Objective: To explore the clinic value of ultrasonogram in detecting fetal ductus arteriosus aneurysm(DAA) on the third trimester of pregnancy. Methods: Forty-seven fetal subjects who were diagnosed with DAA were enrolled in this study. Thirty-five fetal subjects with normal ultrasound result were included as control group. Using echocardiography, ductus arteriosus diameter(DAD) and peak-systolic velocity(PSV) of ductus arteriosus in these two groups were obtained. DAD, PSV, checking time, gestational age, birth weight and maternal age were compared between the two groups. All the subjects underwenta neonatal echocardiogram on the 3rd days after birth to observe the ductus arteriosus. Neonates with abnormal ductus arteriosus were followed up by echocardiogram. Results: There were no significant differences ingestational age, birth weight, maternal age and checking time between the two groups. DAD and PSV in group DAA were higher than those in control group. DAA group had a high incidence of abnormal ductus arteriosus on the 3rd days after birth. Receiver operating characteristic curve analysis revealed that DAD≥9.15 mm can be a good indicator for the abnormal ductus arteriosus with sensitivity of 89.5% and specificity of 75.0%. During the echocardiographic follow-up, all the abnormal ductus arteriosus recovered within 3 months except one case lost. None of the cases had complications related to ductus arteriosus. Conclusion: Echocardiographic parameter obtained from ductus arteriosusprenatally can be a predictor for the occurrence of the abnormal ductus arteriosus after birth.
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Received: 12 April 2019
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