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期刊信息  
创刊日期：1990年
主管单位：中国人民共和国卫生部
主办单位：中国医学影像技术研究会
　　　　　中国医科大学
承办单位：中国医科大学附属盛京医院
　　　　　辽宁省医学影像学会
编辑出版：《中国临床医学影像杂志》
　　　　　编辑部
刊　　期：月刊
2015 Vol. 26, No. 2
Published: 2015-02-20
 
       论著
77 Clinical application value of MR dacryocystography using 3D FIESTA to analyze the cause of epiphora
WANG Yue;ZHOU Jun;CHEN Lin-lin;LI Dan;LIU Xue;ZHU Yue;LI Cong
DOI:
Objective: To explore the value of MR dacryocystography using three-dimensional fast imaging employing steady-state acquisition(3D FIESTA) to analyze the cause of epiphora. Methods: Fifty epiphora patients(64 epiphora sides and 36 healthy sides) underwent MRI lacrimal examination. 0.9% NaCl saline was dropped to bilateral conjunctival sac four times before the exam. The scanning sequences included 3D FIESTA, three-dimensional fast recovery fast spin echo(3D-FRFSE) and fast recovery fast spin echo(FRFSE T2WI). The original images were processed with curve and maximum intensity projection(MIP). The structure around lacrimal ducts was observed and the reason and obstruction position of lacrimal ducts were ananlyzed. All patients underwent expert endoscopy examination and treatment within one week after the MRI scanning. 3D FIESTA, 3D-FRFSE and FRFSE T2WI results were compared with endoscopy results. Results: Compared with endoscopy results of 64 epiphora sides, 3D FIESTA could display the cause and position of obstruct in 61 sides(95.3%), FRFSE T2WI could display the cause and position of obstruct in 53 sides(82.8%), 3D-FRFSE could not display the cause of obstruct, but could display the obstruct position in 42 sides(65.6%). 3D FIESTA obviously preceded FRFSE T2WI and 3D-FRFSE, and the difference was statistically significant（χ2=14.135, P<0.05）. Two lacrimal dysfunction and 1 stenosis of punctum were missed by all these three techniques. Conclusion: 3D FIESTA obviously precedes 3D-FRFSE and FRFSE T2WI for analysis of the cause of epiphora, and it has important effect on choice of clinical treatment plan.
2015 Vol. 26 (2): 77-80 [Abstract] ( 538 ) HTML (0 KB)  PDF  (0 KB)  ( 187 )
81 MRI and MSCT findings of persistent falcine sinus
WU Bing-bing;LI Tao-ling;GENG Ran;HU Kai
DOI:
Objective: To investigate the MRI and MSCT characteristics of persistent falcine sinus, in order to improve the understanding and diagnosis of it． Methods: Clinical, MRI and MSCT data were collected from 17 patients with persistent falcine sinus confirmed by MRI and MSCT from January 2005 to July 2014． Results: MRI cerebral conventional examination was performed in 9 cases, and T2WI sagittal view showed an enlargement vascular flow void signal arising from the great cerebral vein and draining into the superior sagittal sinus in its middle and posterior third part. Magnetic resonance venous imaging(MRV) clearly showed the great cerebral vein draining into the superior sagittal sinus through the opening falcine sinus in 2 cases． Enhanced T1WI also clearly showed the superior sagittal sinus connected with the cisternae venae magnae cerebri by an enhanced blood vessel in 1 case． Five patients underwent CTA, and falcine sinuses were seen as ribbon or yardstick-like vascular structures between the vein of Galen or straight sinus and the posterior third part of the superior sagittal sinus. Conclusion: MRI and MSCT imaging of persistent falcine sinus is characteristic． Conventional MRI combined with MRV, enhanced MRI and MSCT can show the appearance more clearly, position of the persistent falcine sinus and its relationship with surrounding structures, contributing a lot to its comprehensive evaluation．
2015 Vol. 26 (2): 81-83 [Abstract] ( 603 ) HTML (0 KB)  PDF  (0 KB)  ( 208 )
84 Clinical value of 18F-FDG PET/CT accumulations for pinpointing the best location in CT guided percutaneous lung puncture biopsy
CHEN Chang-chun;HU Xiao-yan;CHEN Hao;QIU Da-sheng;LIU Yu-lin
DOI:
Objective: To analyze the collaborative application value of 18F-FDG PET/CT in CT guided lung percutaneous needle biopsy. Methods: A retrospective analysis of 22 patients who underwent both 18F-FDG PET/CT checking and CT-guided chest percutaneous puncture biopsy from 2013 to 2014 was done. The lung puncture target was mainly selected according to 18F-FDG PET/CT imaging. All of the cases received multi-slice spiral CT guided percutaneous lung puncture biopsy, surface located by grid markers. Combined with pathological and follow-up results, the collaborative diagnostic value of 18F-FDG PET/CT accumulations for pinpointing the best location in CT guided percutaneous lung puncture biopsy was studied. Results: 40.9%(9/22) of the high uptake area of lesions were located on the edge or eccentric place, and puncture target spot was adjusted correspondingly. All of the 22 cases of biopsy were performed one time successfuly. The complications were slight pneumothorax in 3 cases and little pulmonary hemorrhage in 6 cases, without hemoptysis. There were 13 cases of adenocarcinoma, 5 cases of squamous cell carcinoma, 1 case of small cell carcinoma, 2 cases of inflammatory granuloma, and 1 case of fungal infection. Compared with the postoperative and long-term follow-up, only one case of lung cancer was misdiagnosed as inflammatory pseudotumor. The accuracy rate of single percutaneous lung puncture biopsy was 95.65%. The positive predictive value and negative predictive value, sensitivity, specificity were 100%, 66.7%, 95%, 100%, respectively. Conclusion: 18F-FDG PET/CT image can help to select the target of percutaneous lung biopsy, and to improve the accuracy of biopsy, which has important clinical value.
2015 Vol. 26 (2): 84-87 [Abstract] ( 727 ) HTML (0 KB)  PDF  (0 KB)  ( 167 )
88 The comparative study between CT and color Doppler ultrasonography for the diagnostic value of hepatoblastoma
LI Jie;CHEN Jing-jing;LI Qiang;BI Wei-qun;XU Wen-jian
DOI:
Objective: To analyze the different imaging findings of epithelial hepatoblastoma(HB) and mixed HB, and to assess the value of CT and color Doppler ultrasonography in the diagnosis of epithelial HB and mixed HB in infants. Methods: CT and color Doppler ultrasonography findings of epithelial HB and mixed HB were evaluated retrospectively in 45 patients with histological confirmation. Accuracies of CT and color Doppler ultrasonography of them were compared. Results: Epithelial HB contained less calcification. And more calcification was discovered in mixed HB. There was significant difference in ratio of calcification in epithelial HB and mixed HB(χ2=13.6, P<0.05). Color Doppler ultrasonography showed high-level echo inside mixed HB lesions. And low-level echo signal was showed in epithelial HB lesions. There was significant difference in intensity of epithelial HB and mixed HB(χ2=12.00, P<0.05). Conclusion: Epithelial HB and mixed HB have characteristics on CT and ultrasound images.
2015 Vol. 26 (2): 88-90 [Abstract] ( 697 ) HTML (0 KB)  PDF  (0 KB)  ( 204 )
91 Study of anatomy of right hepatic vein and accessory right inferior hepatic vein with 128-MSCT angiography
LU Tao;PU Hong;YANG Cheng;PU Nuo
DOI:
Objective: To assess the anatomy of right hepatic vein and accessory right inferior hepatic vein with 128-MSCT angiography. Methods: 432 patients underwent 128-MSCT abdominal CT scan. All data were reconstructed to observe the anatomic details of the hepatic veins. Results: According to Nakamura’s classification of hepatic veins, 274 patients were classified as type Ⅰ(63.43%）, 108 patients were classified as type Ⅱ(25%）, and 50 patients were classified as type Ⅲ(11.57%）. The initial diameter of right hepatic vein was (10.68±3.18) mm, and the length of trunk was (10±2.37) cm. 114 accessory right inferior hepatic vein were found in 96 patients. The initial diameter of the accessory right inferior hepatic vein was (4.43±1.48) mm, and the length of trunk was(6.34±2.22) cm. Two accessory right inferior hepatic veins were found in 18 patients. The distance between the openings of the right hepatic vein and the accessory right inferior vein into the inferior vena cava was (4.74±1.28) cm. Conclusion: 128-MSCT can offer detailed anatomy of the right hepatic vein and the accessory right inferior vein before operation and can supply accurate information for hepatic surgery.
2015 Vol. 26 (2): 91-94 [Abstract] ( 1073 ) HTML (0 KB)  PDF  (0 KB)  ( 191 )
95 Selecting optimal monochromatic level of spectral CT imaging with low concentration contrast media for improving imaging quality of hepatic veins
TONG Zi-bin;LIU Ai-lian;LIU Yi-jun;TIAN Shi-feng;ZHANG Long-min;LIU Jing-hong;PU Ren-wang
DOI:
Objective: To investigate the effect of spectral CT monochromatic images with low concentration contrast media for improving imaging quality of the hepatic veins. Methods: One hundred and fifty-one patients from March 2013 to January 2014 in our hospital underwent spectral CT examination of the full abdomen. According to the first scan time, patients(BMI＞25 kg/m2) were randomly divided into group A with spectral CT optimal monochromatic imaging and low concentration contrast media(270 mgI/mL) and group B with conventional imaging and high concentration contrast media(350 mgI/mL). During portal phase, conventional images and optimal monochromatic images with slice thickness of 1.25 mm were obtained, and volume rendering(VR) and maximum intensity projection(MIP) were created to show the hepatic venography. Independent t-test was used to compare the hepatic venography. And the liver parenchyma, image noise, vein-to-liver contrast-to-noise ratio(CNR) between the two image data sets were compared. The overall imaging quality was evaluated on a five-point scale by two radiologists. Inter-observer agreement in subjective image quality grading was assessed by Kapppa statistics. Mann-Whitney U test was used to compare the image quality score of the hepatic venography between the two groups. The CTDIvol of the two groups were recorded, and the difference between group A and group B was compared by independent t-test. The total amount of iodine was calculated and compared. Result: The monochromatic images at 49～51 keV were found to demonstrate the optimal CNR for the hepatic venography. In group A, CT values of the left hepatic vein, the middle hepatic vein, the right hepatic vein, liver parenchyma, the difference between hepatic veins and liver parenchyma, and the image noise were (335.29±68.45) HU, (343.16±73.95) HU, (327.80±76.22) HU, (187.74±31.98) HU, (147.39±48.91) HU, (155.26±56.68) HU, (139.90±55.19) HU and (39.12±10.04) HU, respectively. Those in group B were (194.82±33.60) HU, (196.62±36.11) HU, (190.60±33.61) HU, (115.89±16.94) HU, (78.93±27.92) HU, (80.73±28.44) HU, (74.71±26.03) HU and (33.82±8.94) HU, respectively. The vein-to-liver CNRs for group A and group B were 3.93±1.80, 4.35±2.29, 3.91±2.08, 2.40±0.85, 2.44±0.82 and 2.26±0.75, respectively. The data of group A were all significantly higher than group B(P＜0.05). Kappa statistics demonstrated a good inter-observer agreement(Kappa values＞0.8). The image quality scores of the hepatic venography of the two groups were 3.43±0.58 and 3.48±0.68. There was no significant difference between the two groups. The CTDIvol of the two groups were (16.87±0.00) mGy and (15.74±5.26) mGy, respectively, and there was no significant difference between the two groups. The total amount of iodine of the two groups were 27 000 mg and 35 000 mg. Group A was 22.86% lower than group B. Conclusion: For patients with BMI＞25 kg/m2, in the premise of reducing the concentration of contrast agent, spectral CT monochromatic imaging can improve the imaging quality of the hepatic veins without significant increase of radiation exposure.
2015 Vol. 26 (2): 95-98 [Abstract] ( 537 ) HTML (0 KB)  PDF  (0 KB)  ( 340 )
99 Imaging findings of abdominal endodermal sinus tumor in children
WU Hui-ying;XU Wen-biao;TIAN Jin-sheng;AI Bin;LI Jian-ming
DOI:
Objective: To evaluate imaging findings of abdominal endodermal sinus tumor(EST) in children. Methods: Thirty-six cases of pelvic and abdominal EST were retrospectively reviewed from 2008 to 2013. Clinical data and CT findings were analyzed. All cases were confirmed by operation and pathology. Results: Mean age of the patients was 2 years and 3 months(ranging from 5 months to 10 years old) and 30 patients were less than 3 years old. 27 females and 9 males were included. The tumors were located in gonads in 4 cases(3 cases in the ovary and 1 case in the cryptorchidism), and out of the gonads in 32 cases, especially in sacrococcygeal region(17 cases) and pelvic and abdominal cavity(10 cases). 12 cases had metastasis, including 6 cases of lymphatic metastases and 12 cases of infiltration and hematogenous metastases. 6 patients relapsed within 2 years. CT manifestations: mean size of the tumors was 6 cm(1～10 cm). 25 tumor were greater than 5 cm. 20 tumors showed morphologically irregular and 16 were regular. 31 cases revealed solid mass on plain CT scan and 5 cases revealed cyst-solidary mass. All tumors showed some tiny vessels and irregular reticular enhancement in post-contrast CT scan. Later, they showed nodular and flocculent enhancing around the tumor. Conclusion: EST in abdomen is a highly malignant germ cell tumor in children. CT findings have some features and have important value in diagnosis.
2015 Vol. 26 (2): 99-104 [Abstract] ( 694 ) HTML (0 KB)  PDF  (0 KB)  ( 191 )
105 The clinical application of low dose delay scan in MSCTU for urologic disease
ZHU Yu-chun;XING Wei;WANG Jian-liang;SHEN Ji-fang
DOI:
Objective: To discuss the diagnostic value of low dose delay scan(tube voltage 100 kV+CARE Dosed 4D) in multi-slice helical computed tomography urography(MSCTU), and discuss the diagnostic sensitivity of three different post-processing recombinant technologies(MPR/CPR, MIP, VR) in urologic disease. Methods: 34 cases of patients undertook low dose scan protocol in delay phase(100 kV+CARE Dosed 4D). The 1 mm-thick CT data in the delay phase were restructed by post-processing technology and compared with clinical and pathological diagnosis. Results: In 34 cases of patients, the accuracy of localization and qualitative diagnosis of MSCTU image was 97.1%(33/34) and 91.2%(31/34), respectively. The localization and qualitative diagnostic sensitivity in three different image combinations from high to low was as follows: MSCTU image>CT axial combined with delay image>routine CT axial, and the diagnostic accuracy of localization was higher than the qualitative diagnosis. There was statistically significant difference(P<0.012 5) between MSCTU image and routine CT axial, but not for the rest of the combinations(P>0.012 5). Meanwhile, the localization and qualitative diagnostic sensitivity in three different image post-processing technologies from high to low was as follows: MPR/CPR>MIP>VR. There were statistical significant differences(P=0.000) between MPR/CPR and MIP or VR technology, while not between MIP and VR(P>0.012 5). Conclusion: MSCTU using 100 kV with CARE Dosed 4D technology in excretory phase can not only reduce radiation dose in single phase, but also have higher diagnostic accuracy in localization and qualitative diagnosis. The low dose scan protocol is worth to be widely applied in the clinic of urologic disease.
2015 Vol. 26 (2): 105-110 [Abstract] ( 500 ) HTML (0 KB)  PDF  (0 KB)  ( 169 )
111 Combination of ultrasound and MRI in the diagnosis of fetal posterior fossa anomalies
ZHANG Bo;YANG Tai-zhu;LUO Hong
DOI:
Objective: To investigate the role of combined ultrasound and MRI in the prenatal diagnosis of fetal posterior fossa anomalies and to verify its clinical value. Methods: The imaging data of cases suspected of fetal posterior fossa anomalies by prenatal ultrasound in our hospital were analyzed retrospectively from January 2011 to December 2012. We reviewed prenatal ultrasonography, MRI imaging, and outcome of all the cases after delivery as well as early postnatal imaging studies. Results: 27 cases suspected of fetal posterior fossa anomalies by fetal sonography underwent MRI examination during the study period. 9 were found to have normal posterior fossa structures by fetal MRI. In the remaining 18 cases(66.7%), posterior fossa abnormalities suspected by fetal sonography were confirmed by fetal MRI, of which 11 were live-born and 10 underwent postnatal MRI. There was complete agreement in fetal and postnatal MRI diagnoses in 5 infants (50%). In 2 cases (20%) fetal and postnatal MRI diagnoses disagreed and postnatal MRI revealed additional anomalies in 3 cases(30%). Conclusion: Ultrasonography is an effective method for prenatal identification of fetal posterior fossa anomalies. Antenatal MRI serves to confirm the sonographic findings as well as offering additional diagnostic information. However, postnatal MRI follow-up should be strongly emphasized.
2015 Vol. 26 (2): 111-113 [Abstract] ( 675 ) HTML (0 KB)  PDF  (0 KB)  ( 194 )
114 The MSCT diagnosis of seminoma in intraabdominal undescended testis
MU Hua-guo;SANG Ling;WANG Zhong-ping;CHEN Ping-you;CHEN Hai-bo;CHEN Lun-gang
DOI:
Objective: To assess the imaging features of MSCT in diagnosing seminoma in intraabdominal undescended testis, and to strengthen the understanding of the disease． Methods: MSCT images of 15 cases of seminoma of abdominal testis proved by pathology and surgery were analyzed, and the results were compared with pathology. All of the 15 cases underwent plain and enhanced MSCT scanning. Results: All of the 15 cases were male, age ranged from 19 to 38 years old, with an average age of 29 years. The lesions were located in the pelvic cavity, with cystic change, clear realm and uneven density. Solid component was located in the edge of the mass, and irregular necrosis of low density was seen in the center. Stripy separations were seen in all the masses, without fat and calcification. Enhancement was inhomogeneous, and the margin of solid component was slightly enhanced, without strengthening of the central irregular low density necrosis. Thickened and tortuous testicular arteries were seen in 11 cases in the arterial phase, and thickened and twisted testicular veins were seen in 9 cases in the venous phase. Ipsilateral testis was abscent, 12 cases in the right and 3 cases in the left. CT staging was consistent with operation and pathology. Conclusion: Seminoma in intraabdominal undescended testis is rare, and the clinical symptoms are insidious. When a young male patient found a mass in the lower abdomen, testicular absence or not should be carefully checked, being alert to the possibility of senminoma in intraabdominal undescended testis. Thickened testicular arteries and?蛐or draining veins on enhanced CT can help the diagnosis, and early finding is important for the prognosis.
2015 Vol. 26 (2): 114-117 [Abstract] ( 532 ) HTML (0 KB)  PDF  (0 KB)  ( 224 )
118 Monitoring vascular complications on autogenous arteriovenous fistulas in hemodialysis patients: value of high-frequency ultrasound
DING Hong;GU Qi-lan;ZHU Yu-li;ZHOU Zhi-ying;BAI Shou-jun
DOI:
Objective: To assess the value of high-frequency ultrasound in monitoring vascular complications on autogenous arteriovenous fistulas(AVF) in hemodialysis patients. Methods: Eighty-one patients with clinically normal hemodialysis access were examined with color Doppler ultrasound. The structure of AVF, peak systolic velocity, resistance index(RI) and blood flow volume of branchial artery were recorded. Results: Among 81 AVF patients, 45(55.6%) were normal in structure, and 36(44.4%) were abnormal including 14 venous dilatation, 12 thrombosis, 9 arterial steal symptom and 1 pseudoaneurysm. There were 8(9.9%) cases diagnosed as AVF stenosis due to thrombosis. The mean flow volume of all patients was (1 146±410) mL/min(203~2 390 mL/min). The incidence of vascular complications was higher in low(<800 mL/min) and high(≥1 500 mL/min) blood flow volume groups than in the middle volume group(P<0.05). The blood flow volume in stenosis cases was (375±124) mL/min, which was significantly lower than no complication group(P<0.05). There was also statistically significant difference in the diameter of stenostic vessels and the RI of radial artery and anastomosis between the stenosis group and no complication group(P<0.05). Conclusions: There are some vascular complications in clinically normal AVF patients, which can be monitored with high-frequency ultrasound based on its structure, blood flow volume and hemodynamics measurement regularly. Special emphasis should be put when the blood flow volume is <800 mL/min on ultrasound in order to avoid AVF dysfunction.
2015 Vol. 26 (2): 118-121 [Abstract] ( 569 ) HTML (0 KB)  PDF  (0 KB)  ( 253 )
       综述
122 Progress of the application of MR diffusion tensor imaging in skeletal muscle
GE Xiao-xue;SUN Hong-zan;SUN Ying-wei;GUO Qi-yong
DOI:
2015 Vol. 26 (2): 122-124 [Abstract] ( 618 ) HTML (0 KB)  PDF  (0 KB)  ( 191 )
       短篇论著
125 The characteristic of childhood leukemia complicated with cerebral hemorrhage and the application value of SWI
XIANG Yong-hua;JIN Ke;CHEN Hua;GAN Qing
DOI:
2015 Vol. 26 (2): 125-128 [Abstract] ( 687 ) HTML (0 KB)  PDF  (0 KB)  ( 240 )
128 Consistency between CTA and DSA in evaluation of artery stenosis in patients of moyamoya disease
WANG Qiang;NIU Yu-jun
DOI:
2015 Vol. 26 (2): 128-130 [Abstract] ( 604 ) HTML (0 KB)  PDF  (0 KB)  ( 210 )
131 Cerebral microhemorrhage foci: the study of multiple sequences imaging by 3.0T MRI
ZHANG Yu;WANG Cheng-jian;YANG Jing-zhen;HUO Ying-jie;ZHAO Yong-qiang
DOI:
2015 Vol. 26 (2): 131-134 [Abstract] ( 659 ) HTML (0 KB)  PDF  (0 KB)  ( 233 )
134 Value of CT in the diagnosis of coronary artery fistula
KONG Shu-hong;YUE Xue-wang;KONG Sheng
DOI:
2015 Vol. 26 (2): 134-136 [Abstract] ( 633 ) HTML (0 KB)  PDF  (0 KB)  ( 209 )
137 Diagnostic value of CEUS in ovarian solid-cystic lesions
ZHANG Ya-li;WANG Li;ZHANG Run;LIU Shuang-yan
DOI:
2015 Vol. 26 (2): 137-138 [Abstract] ( 583 ) HTML (0 KB)  PDF  (0 KB)  ( 160 )
139 Diagnostic value of color Doppler ultrasonography and shear wave elasticity on soft tissue hemangiomas
LI Mi;REN Yan;BIAN Dong-lin
DOI:
2015 Vol. 26 (2): 139-140 [Abstract] ( 569 ) HTML (0 KB)  PDF  (0 KB)  ( 212 )
141 The therapeutic value of ultrasound guided fine needle puncture for the treatment of tendon disease
WU Jing;LIU Hao-yue;PAN Sheng-nan;FU Yu
DOI:
2015 Vol. 26 (2): 141-142 [Abstract] ( 549 ) HTML (0 KB)  PDF  (0 KB)  ( 175 )
       影像技术
143 Clinical application of dual energy imaging technology of dual-source CT in the bone and joint with internal metal fixer
CAO Yong-jie;ZHOU Jun;JIANG Nan
DOI:
2015 Vol. 26 (2): 143-145 [Abstract] ( 679 ) HTML (0 KB)  PDF  (0 KB)  ( 188 )
       病例报告
146 CT diagnosis of nasal extranodal NK/T-cell lymphoma associated with laryngeal NK/T-cell lymphoma: report of one case
LIU Qiang;PAN Shi-nong
DOI:
2015 Vol. 26 (2): 146-147 [Abstract] ( 638 ) HTML (0 KB)  PDF  (0 KB)  ( 242 )
147 Ultrasonic diagnosis of diverticulitis in pharyngeal esophagus: report of one case
SONG Yan-peng;NIAN Qi-yu;GE Gui-xia
DOI:
2015 Vol. 26 (2): 147-147 [Abstract] ( 575 ) HTML (0 KB)  PDF  (0 KB)  ( 216 )
148 Ultrasonic diagnosis of inguinal incarcerated hernia containing uterus and ovary in female infant: report of one case
ZHANG Zhan
DOI:
2015 Vol. 26 (2): 148-148 [Abstract] ( 517 ) HTML (0 KB)  PDF  (0 KB)  ( 176 )
149 Extraskeletal osteosarcoma of lower anterior abdominal wall with generalized metastases: report of one case
TAO Hai-bo;LI Kun;DING Ying-ying
DOI:
2015 Vol. 26 (2): 149-151 [Abstract] ( 647 ) HTML (0 KB)  PDF  (0 KB)  ( 530 )
151 Primary testicular lymphoma: report of two cases
LIN Lin-lin;QIAO Peng-gang;LI Gong-jie;LI Yang;SHUANG Ping;SI Wen
DOI:
2015 Vol. 26 (2): 151-152 [Abstract] ( 536 ) HTML (0 KB)  PDF  (0 KB)  ( 191 )
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