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期刊信息  
创刊日期：1990年
主管单位：中国人民共和国卫生部
主办单位：中国医学影像技术研究会
　　　　　中国医科大学
承办单位：中国医科大学附属盛京医院
　　　　　辽宁省医学影像学会
编辑出版：《中国临床医学影像杂志》
　　　　　编辑部
刊　　期：月刊
2012 Vol. 23, No. 12
Published: 2012-12-20
 
       论著
837 Differential diagnosis of pulmonary tuberculomas and malignant nodules using18F-FLT and 18F-FDG PET/CT imaging
CHEN Wen-xin;LIN Mei-fu;TIAN Jia-he;YANG Xiao-feng;YU Li-juan;WANG Xue-mei;XIN Jun;FENG Hui-ru;CHEN Ping;ZHAO Zhou-she;GUO Shen;CHEN Guo-bao
DOI:
Objective: To investigate the diagnostic efficacies of 18F-FLT and 18F-FDG PET/CT in pulmonary nodules, focusing on diagnosis and differential diagnosis of pulmonary tuberculomas and malignant nodules. Materials and Methods: 163 patients with solitary pulmonary nodules undergoing dual-tracer imaging were certified by histological findings. The patients were collected from a multicenter clinical trial and were divided into the group of pulmonary tuberculoma(n=29), group of other benign nodule(n=48) and group of malignant nodule(n=88). The images were read in a standardized, blind, collective reading. The standardized uptake value(SUV) of 18F-FDG and 18F-FLT were compared and analyzed. Results: The SUVs of FDG and FLT in groups of malignant nodule, tuberculoma and other benign nodule were in a decreasing order. Both SUVFDG and SUVFLT showed significant difference in the group of malignant nodule and tuberculoma(P<0.001). ROC curve showed that a SUV cutoff of 5.9 on FDG PET/CT and 2.4 on FLT PET/CT provided the best separation of tuberculomas and malignancies. FLT PET/CT had higher diagnostic efficacy than FDG PET/CT(P<0.001). The ratio between SUVs of 18F-FLT and 18F-FDG improved the diagnostic efficacy in comparison with single tracer imaging. Conclusions: Dual-tracer imaging using 18F-FDG/18F-FLT PET/CT provides a better diagnostic efficacy in these clinically challenging patients with pulmonary lesions. A SUV cutoff of 5.9 on FDG PET/CT and 2.4 on FLT PET/CT provide the best separation of tuberculomas and malignancies. The ratio between SUVs of 18F-FLT and 18F-FDG provides great potential benefits in separating tuberculomas and malignancies.
2012 Vol. 23 (12): 837-840 [Abstract] ( 874 ) HTML (0 KB)  PDF  (0 KB)  ( 203 )
841 Endoscopic ultrasonography and transabdominal ultrasonography in preoperative staging of gastric cancer
ZHU Hao-hui;YUAN Jian-jun;CHEN Ji-yun;TIAN Peng;BAI Yang-qiu;FENG Yan;REN Ying
DOI:
Objective: To investigate the diagnostic value of endoscopic ultrasonography and transabdominal ultrasonography in preoperative staging of gastric cancer. Method: EUS and US were carried out in 134 patients of gastric cancer diagnosed by gastroscope and pathology. The invasion depth, range and boundary of the lesions were observed. Local lymph node metastasis and the neighboring or remote organs metastasis were recorded. The results of EUS and US were compared with the results of operation and pathology. Results: The accuracy of US was similar to EUS in T staging(75.37% vs 76.12%), but the accuracy of EUS in T4 staging was obviously lower than US(29.17% vs 79.17%). The accuracy of US and EUS in N staging was 50.75% and 69.40%, with a statistical difference between them(P<0.05). US was slightly lower than EUS in N0 and N1 staging(76.92% vs 84.61%; 69.64% vs 71.43%), but there was no statistical difference(P>0.05). The accuracy of US was obviously higher than EUS in N2 and N3 staging(68.29% vs 34.15%; 66.67% vs 12.50%), and there was a statistical difference(P<0.05). US was obviously superior to EUS in M1 stage. The accuracy of M1 staging by US and EUS was 83.33% and 16.67% respectively(P<0.05). The accuracy of EUS and US in TNM staging was 64.18% and 66.42% respectively, but the accuracy of EUS combined with US increased to 79.10%. Conclusion: EUS and US can both be used in T1, T2 and T3 staging, and the accuracy of US is obviously higher than EUS in T4 staging. The accuracy of EUS is slightly higher than US in N0 and N1 staging, but there is also no statistic difference. US is obviously superior to EUS in N2, N3 and M1. Therefore, EUS combining with US can obviously increase the accuracy of TNM staging for gastric cancer patients.
2012 Vol. 23 (12): 841-844 [Abstract] ( 763 ) HTML (0 KB)  PDF  (0 KB)  ( 199 )
845 Diffusion imaging of liver cystic echinococcosis and analysis of cyst fluid: a control study
LI Hui;QU Yuan;JIANG Jie;LIU Yan
DOI:
Objective: To help the diagnosis of liver hydatid cyst, which is difficult to identify by imaging or serological test alone, by diffusion imaging and biochemical analysis in a group of patients with liver hydatid cyst and non-parasitic cysts, and to study the difference of metabolites, enzymes, glucose and protein concentration of the cystic fluid between hydatid cyst and non-parasitic cysts. Materials and Methods: Diffusion imaging was performed in 29 cases of hydatid cysts and 17 cases of simple cysts. Through echoguided method and surgery, we obtained cystic liquid from 13 cases of hydatid cyst and 7 cases of non-parasitic cysts. The cystic liquid was subjected to the following investigations: evaluation of the macroscopic appearance, determination of the concentration of glucose, nitrogen, sodium, potassium, chlorine, calcium, bilirubin, proteins, and parasitological and cytological evaluation of the sediment. Result: ADC value of hydatid cysts was lower than that of simple cysts, with significant difference. Concentration of glucose, calcium and blood urea nitrogen in 13 cases of liver hydatid cyst fluid was higher than non-parasitic cysts, with significant difference. Conclusion: This study indicates that diffusion imaging can help to identify liver hydatid cysts and simple cysts, especially early hydatid cysts. Sampling of the liquid of non-neoplastic cysts of the liver can add information for a correct diagnosis of non-parasitic cysts, hydatid cysts and pseudocysts. Glucose of hydatid cyst fluid is higher than simple cyst, but not for protein content, suggesting glucose macromolecules absorbing water molecules as a reason of restricted diffusion.
2012 Vol. 23 (12): 845-848 [Abstract] ( 803 ) HTML (0 KB)  PDF  (0 KB)  ( 159 )
849 The correlation of abdominal fat distribution and diabetes mellitus
ZHU An-hui;CUI Bin;YAO Dan;ZHANG Xiao-jin
DOI:
Objective: To evaluate the correlation of the abdominal fat distribution and diabetes mellitus. Methods: The research objects were divided into two groups: group one included 176 cases, in which there were 92 cases of type Ⅰ diabetes and 84 cases of type Ⅱ diabetes. The control group included 50 cases of healthy people. The differences of totally abdominal fat content(TA), visceral adiposity(VA), superficial adiposity(SA), VA/SA, body mass index(BMI), triglycerides(TG), high-density lipoprotein(HDL) cholesterol, total cholesterol(Tch), low density lipoprotein(LDL) among type Ⅰ diabetes group, type Ⅱ diabetes group and control group and the correlations of these parameters were analyzed. Results: There were significant differences in TA, VA, SA, VA/SA, BMI, TG and HDL between type Ⅰ diabetes and type Ⅱ diabetes. No significant differences of Tch and LDL were found. TA, VA, SA and VA/SA were positively correlated with the onset of type I and type Ⅱ diabetes. In type Ⅰ diabetes, VA was negatively correlated with HDL, but positively correlated with BMI and AGE. SA was positively correlated with BMI and SEX. In type Ⅱ diabetes, SA was positively associated with TG and SEX, while VA was positively correlated with BMI, AGE and TG. Conclusion: The technology of CT measurement of abdominal fat content is simple and reliable. Abdominal fat content was positively associated with diabetes onset, and abdominal fat content of different types of diabetes have different factors related, which is of certain guidance for making personalized treatment.
2012 Vol. 23 (12): 849-852 [Abstract] ( 641 ) HTML (0 KB)  PDF  (0 KB)  ( 246 )
853 A study of CT perfusion imaging of cervical cancer on Aquilion ONE 320
QIAN Hao-chu;GUO Wen-li;WANG Si-liang;HU Tian-yu;WU Rong
DOI:
Objective: To investigate the parameters obtained with 320 CT perfusion imaging in cervical cancer and the clinical application. Methods: Thirty-six cases of cervical cancer patients were scanned with Aquilion ONE 320 CT, including 16 cases of stage Ⅰ~Ⅱ cervical cancer and 20 cases of stage Ⅲ~Ⅳ cervical cancer. Fifteen cases of parametrial normal tissues were considered as a control group. Time-density curves(TDC), as well as perfusion parameters, including blood flow(BF), blood volume(BV) and permeability surface(PS) were post-processed by perfusion CT software package. Results: BF, BV and PS were higher in the stage Ⅰ~Ⅱ and Ⅲ~Ⅳ cervical cancer groups than those in the parametrial normal control group; BF, BV and PS were higher in the stage Ⅲ~Ⅳ group than those in the Ⅰ~Ⅱ stage cervical cancer group, with statistically significant differences(P<0.05). Perfusion parameters enhanced with the increase of the tumor stage. Conclusions: 320 CT perfusion imaging in cervical cancer provides a new method to reliably demonstrate the parameters of perfusion imaging and internal perfusion, thus, it is clinically significant for tumor staging, prognosis and evaluation of tumor therapy.
2012 Vol. 23 (12): 853-855 [Abstract] ( 877 ) HTML (0 KB)  PDF  (0 KB)  ( 477 )
856 Clinical application and research of diffusion weighted MR imaging in complex ovarian tumors
CUI Yan-fen;LI Wen-hua;ZHU Ming-jie;WANG Deng-bin;ZHANG Ping;ZHANG Zhong-yang;CHU Cai-ting
DOI:
Objective: To retrospectively estimate the diagnostic accuracy of diffusion-weighted MR imaging(DWI) in complex solid and cystic adnexal masses, and to determinate the optimal cutoff value for differentiating benign and malignant ovarian tumors. Materials and Methods: Eighty-four patients underwent DWI. The adnexal lesions were examined for several features including size, shape, character(solid-cystic), signal intensity, and enhancement. The mean ADC value of the solid components was measured and assessed for each ovarian mass. Receiver operating characteristic(ROC) was used to assess ability of ADC in differentiating benign versus malignant complex adnexal masses. Results: The mean ADC value was (1.456±0.297)×10-3 mm2/s and (0.929±0.215)×10-3 mm2/s for the benign and malignant masses respectively, and there was significant difference between them(P﹤0.01). The ROC results suggested that an ADC value ≥1.225×10-3 mm2/s might be an optimal cutoff value for differentiating benign and malignant tumors, with sensitivity of 86.7%, specificity of 94% and AUC of 92.1%，respectively. Conclusion: DWI is a useful supplement to conventional MRI. The measurement of ADC values of the solid components is especially useful for differentiating benign from malignant ovarian masses.
2012 Vol. 23 (12): 856-859 [Abstract] ( 598 ) HTML (0 KB)  PDF  (0 KB)  ( 202 )
860 A correlation study of Gleason score and the diagnostic accuracy of MRS inprostate cancer based on pathological section
CHENG Zi-jun;ZHAO Yang;BAI Mei;HAN Yue;LI Xin-zi
DOI:
Objective: To investigate the diagnostic accuracy of magnetic resonance spectroscopy(MRS) in prostate cancer(PCa) and its correlation with Gleason score by making a comparative study of prostate MRS and the corresponding pathological section. Methods: Radical perineal prostatectomy was performed in 5 patients with PCa. Before operation, all the patients underwent prostate MRS scanning. According to the widest cross section in prostate 3D-MRS image, the interested layer of radical prostatectomy specimens were selected and sliced. On the basis of MRS voxels, the interested layer was cut into 15~35 pieces equally. Each piece was numbered in agreement with the order of MRS voxels and made into pathological sections. The diagnosis of MRS was compared to pathological finding in the same area. The correlation between the ratio of (choline+creatine)/citrate(CC/C) and Gleason score was evaluated. According to the difference of Gleason score, the PCa regions were divided into several groups. The relationship of Gleason score and diagnostic accuracy of MRS in PCa was researched by Spearman’s rank correlation analysis. Results: 90 regions with valid pathologic diagnosis were obtained in total. Using CC/C>0.86 as the diagnostic standard, 65 cancer-affected regions and 25 cancer-free regions were diagnosed by MRS, among which the results consistent with pathologic diagnosis were 59 and 14, respectively. There was a significant positive correlation between the ratio of CC/C and Gleason score of PCa(r=0.746, P=0.000). In group 1(Gleason score=6), the diagnostic accuracy of MRS in PCa was 50%. In group 2(Gleason score=7), the diagnostic accuracy was 53.8%. In group 3(Gleason score=8), the diagnostic accuracy was 72%. In group 4(Gleason score=9) and group 5(Gleason score=10), the diagnostic accuracy was 100%. Spearman’s rank correlation analysis showed that the diagnostic accuracy of MRS in PCa was significant positively correlated to the Gleason score(r=0.223， P=0.034). Conclusion: The correlation between the diagnostic accuracy of MRS in PCa and Gleason score was significant positive. The diagnostic accuracy of MRS in PCa may gradually increased with the malignant degree of PCa.
2012 Vol. 23 (12): 860-863 [Abstract] ( 761 ) HTML (0 KB)  PDF  (0 KB)  ( 197 )
864 The analysis of clinical effect of mechanical aspiration and thrombolytic treatment foracute mixed lower extremity deep venous thrombosis
ZHANG Xi-quan;WANG Yi-ping;ZHU Wei;LI Chang-hai;GUO Feng;DONG Ge;ZHANG Qing
DOI:
Objective: To compare the clinical effect of mechanical aspiration and thrombolytic treatment for acute mixed lower extremity deep venous thrombosis(LEDVT). Materials and Methods: The clinical data of 458 patients with acute mixed LEDVT from April 1998 to January 2010 were reviewed. 327 patients(A group) were treated with mechanical thrombus aspiration, among which there were 113 patients combined with iliac vein compression syndrome(IVCS). PTA and stenting were used as auxiliary treatments, and all the patients received small dose of urokinase(UK) thrombolysis and heparin anticoagulation after operation. 131 patients(B group) were treated by systemic thrombolysis and anticoagulation with UK and heparin. Results: After leaving hospital, the difference of circumference 15 cm above and under the knees for bilateral limbs in group A was reduced from (10.51±7.53) cm and (5.86±3.26) cm to (1.34±1.07) cm and (0.93±0.52) cm(ｕ＝21.80, ｕ=27.00)． In Group B, the difference was reduced from (10.68±7.67) cm and (5．52±3．37) cm to (2.89±1.53) cm and (1.72±0.89) cm(ｕ＝11.39, ｕ＝12.45). Patients were followed up for an average of (46±39) months, and the circumference 15 cm under the knees was reduced to (0.53±0.42) cm in group A and (1.42±1.35) cm in group B(ｕ=7.40). The sequelae of edema, pigmentation and ulcer were 27.83％(91/327), 13.15％(43/327) and 0％ in group A, lower than 55.73％(73/131), 83.97％(110/131) and 9.16％(12/131) in group B(ｕ＝3.14, 14.52, 5.58). CDFI found in group A 90.83％ veins regained patency and 73.09％ valves had normal function, which were higher than those in group B (37.41％ and 15.27％, ｕ＝12.04, ｕ＝11.28). The follow-up effect of group A 88.99％ was obviously higher than group B 29.77％(ｕ＝12.74). There were two patients in group B who suffered life-threatening bleeding but no one in group A. Conclusion: For the treatment of acute mixed DVT, especially for protecting the normal valve function, mechanical thrombus aspiration is significantly superior to systemic thrombolysis. To prevent re-thrombosis and improve medium-term and long-term follow-up clinical effect, we should take comprehensive treatments of thrombolysis, anticoagulation, antiplatelet etc.
2012 Vol. 23 (12): 864-869 [Abstract] ( 679 ) HTML (0 KB)  PDF  (0 KB)  ( 157 )
870 The imaging appearances of Schwannomas with spinal bone destruction
ZHANG Li-hua;YUAN Hui-shu
DOI:
Objective: To explore the imaging appearances of Schwannomas with spinal bone destruction and raise the awareness of this tumor. Methods: CT and MRI of 9 cases pathologically confirmed Schwannomas with spinal bone destruction were analyzed retrospectively. Results: Among the 9 cases, 3 cases were located in cervical vertebrae, 4 cases were located in thoracic vertebrae, and 2 cases were located in lumbosacral vertebrae. The boundary of tumors was relatively clear, with lobulated edge. The tumors located in lumbosacral segment were larger than those in cervical thoracic segment. Eight cases were manifested as expanding osteolytic destruction. Remnants of bone crest could be seen in 3 cases. Two cases had sclerotic rims. None had complete bone shell. The intervertebral foramen and sacral foramen were expanded in 4 cases located in cervical and thoracic segment and all cases in the lumbosacral segment. T1-weighted MRI revealed that tumors had homogeneous and low to intermediate signal intensity. The tumors showed heterogeneous signal intensity on T2WI, and demonstrated significant heterogeneous enhancement on post-contrast images. Conclusions: Schwannomas with spinal bone destruction are rare. The imaging appearances of schwannomas are characteristic on CT and MRI. The tumors are lobulated, with expanding osteolytic bone destruction. The signal of tumor is heterogeneous and significant heterogeneous enhancement can be seen on post-contrast images.
2012 Vol. 23 (12): 870-873 [Abstract] ( 622 ) HTML (0 KB)  PDF  (0 KB)  ( 166 )
       综述
874 A study of MR quantification in the assessment of hepatic iron loading
HAO Li;LIU Ai-lian
DOI:
2012 Vol. 23 (12): 874-876 [Abstract] ( 662 ) HTML (0 KB)  PDF  (0 KB)  ( 224 )
       短篇论著
877 CT diagnosis of the large vestibular aqueduct malformation in children
WANG Xiao-qi;ZHANG Shu-tian;YUAN Hong-li;PAN Chun-yan;MA Li
DOI:
2012 Vol. 23 (12): 877-878 [Abstract] ( 641 ) HTML (0 KB)  PDF  (0 KB)  ( 270 )
878 The dynamic enhanced CT in parotid adenolymphomas
CHEN Jian-hua;SHEN Jian-min;SHENG Liang;LI Jun-miao
DOI:
2012 Vol. 23 (12): 878-880 [Abstract] ( 671 ) HTML (0 KB)  PDF  (0 KB)  ( 183 )
881 Value of ultrasound in diagnosing primary breast lymphoma
JIA Zhi-ying;AI Xiu-qing;ZHANG Yin-hua;MA Fu-cheng
DOI:
2012 Vol. 23 (12): 881-882 [Abstract] ( 703 ) HTML (0 KB)  PDF  (0 KB)  ( 241 )
883 The value of ultrasonic E-Tracking imaging in evaluating carotid artery elasticity andits correlation with vascular endothelial function in patients with alcoholic liver disease
LIU Jing-yun;WU Wen-zhi;CHEN Shun-ping;HU Yuan-ping;LIU Xin-ying
DOI:
2012 Vol. 23 (12): 883-884 [Abstract] ( 604 ) HTML (0 KB)  PDF  (0 KB)  ( 419 )
885 Contrast-enhanced ultrasound in the diagnosis of liver hypoechoic lesions
ZHAO Chun-xiao;ZHOU Ai-yun;JIANG Li-ping
DOI:
2012 Vol. 23 (12): 885-887 [Abstract] ( 631 ) HTML (0 KB)  PDF  (0 KB)  ( 365 )
887 Assessment of left atrial function in patients with hypertrophic cardiomyopathy by left atrial tracking technology
HOU Su-yun;QIN Shi-cheng;HUA Shao-hua;CHENG An-ling
DOI:
2012 Vol. 23 (12): 887-889 [Abstract] ( 594 ) HTML (0 KB)  PDF  (0 KB)  ( 168 )
890 Evaluation of left atrial function in patients with hypertrophic cardiomyopathy usingtwo-dimensional speckle tracking echocardiography
YANG Xing-an;WANG Gang;ZHU Tong-wei;DING Xiao-ming
DOI:
2012 Vol. 23 (12): 890-892 [Abstract] ( 620 ) HTML (0 KB)  PDF  (0 KB)  ( 207 )
892 Clinical significance of ultrasound contrast imaging in classification of acute pancreatitis
YANG Hao;YIN Jia-bao;ZHOU Su-fen;LV Jin-yu;ZHONG Jing;GAN Ling;AN Peng
DOI:
2012 Vol. 23 (12): 892-894 [Abstract] ( 618 ) HTML (0 KB)  PDF  (0 KB)  ( 223 )
895 The value of three-dimensional power Doppler imaging in monitoring placental perfusion ofpatients with pregnancy-hypertension
LIU Xue-ling;LUO Feng;LIAN Su;CHENG Ping;LEI Pei;WU Ye-dong;LI Jian;LI Shan-xia
DOI:
2012 Vol. 23 (12): 895-896 [Abstract] ( 690 ) HTML (0 KB)  PDF  (0 KB)  ( 263 )
897 The relationship of fetal nuchal translucency and ductus venous wave withcardiac malformation in early pregnancy
LIU Jie;CHAI Yi-qing;ZHANG Tan
DOI:
2012 Vol. 23 (12): 897-898 [Abstract] ( 757 ) HTML (0 KB)  PDF  (0 KB)  ( 229 )
899 Echocardiographic assessment of pulmonary artery pressure in asphyxia and preterm infants
DU Wei;WANG Hong;LIU Jian-wei
DOI:
2012 Vol. 23 (12): 899-900 [Abstract] ( 625 ) HTML (0 KB)  PDF  (0 KB)  ( 218 )
901 The application transvaginal color Doppler ultrasound to observe the endometrium inthe diagnosis of early ectopic pregnancy
ZHAO Jin;WANG Fang;JIANG Lin;QIN Tian-hua
DOI:
2012 Vol. 23 (12): 901-903 [Abstract] ( 596 ) HTML (0 KB)  PDF  (0 KB)  ( 185 )
903 Diagnosis and treatment of radial nerve entrapment syndrome by ultrasonography
ZHANG Zhan;CHEN De-song;CHEN Wei-min;CHEN Yun-chao;ZHANG Chun
DOI:
2012 Vol. 23 (12): 903-905 [Abstract] ( 619 ) HTML (0 KB)  PDF  (0 KB)  ( 246 )
       病例报告
906 Imaging findings of renal inflammatory myofibroblastic tumor: report of three cases
WANG Mei;ZHANG Long-jiang;LU Li;LU Guang-ming
DOI:
2012 Vol. 23 (12): 906-907 [Abstract] ( 617 ) HTML (0 KB)  PDF  (0 KB)  ( 234 )
907 Pelvic hemangiopericytoma: report of one case
SONG Zhi-guang;JIN Kai-yuan;WANG Feng;LI Bang-guo
DOI:
2012 Vol. 23 (12): 907-908 [Abstract] ( 630 ) HTML (0 KB)  PDF  (0 KB)  ( 230 )
908 Missed diagnosis of incomplete mediastinal uterine combined withunilateral hydatidiform mole by CDFI: report of one case
LI Xiao-hong;WU Jing;ZHONG Shao-wei;LI Bo
DOI:
2012 Vol. 23 (12): 908-909 [Abstract] ( 610 ) HTML (0 KB)  PDF  (0 KB)  ( 201 )
909 Primary non-Hodgkin’s lymphoma of endometrium(T cell): report of one case
WU Yuan-yuan;NIU Jia-zeng;ZHOU Hui-jie;ZOU Ling-hua
DOI:
2012 Vol. 23 (12): 909-910 [Abstract] ( 624 ) HTML (0 KB)  PDF  (0 KB)  ( 202 )
910 Urachal cyst with mucous villous adenoma combined with partialhigh-degree intraepithelial neoplasia: report of one case
ZHANG Sun-yan;YIN Yan
DOI:
2012 Vol. 23 (12): 910-911 [Abstract] ( 664 ) HTML (0 KB)  PDF  (0 KB)  ( 225 )
911 MRI diagnosis of peripheral primitive neuroectermal tumors: report of two cases
JIANG Yan-li;CHEN Gang;YE Jian-jun;MA Qiang-hua
DOI:
2012 Vol. 23 (12): 911-912 [Abstract] ( 632 ) HTML (0 KB)  PDF  (0 KB)  ( 197 )
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