JOURNAL OF CHINA MEDICAL IMAGING

Office Online

Journal Online

Advanced Search

期刊信息

创刊日期：1990年
主管单位：中国人民共和国卫生部
主办单位：中国医学影像技术研究会
　　　　　中国医科大学
承办单位：中国医科大学附属盛京医院
　　　　　辽宁省医学影像学会
编辑出版：《中国临床医学影像杂志》
　　　　　编辑部
刊　　期：月刊

2018 Vol. 29, No. 11 Published: 2018-11-20

	761	The role of multilayer spiral CT perfusion in evaluating the survival of scalp flap after large-area cranioplasty
		ZHU Jian-ping, ZHANG Ming, ZHANG Lei, LIU Yao
		DOI: 10.12117/jccmi.2018.11.001
		Objective: To explore the role of multilayer spiral CT perfusion imaging(MSCTPI) technology in evaluating the survival of covered flap after large-area cranioplasty. Method: Four months after temporal craniectomy, the patients with flap areas about 45 cm2 were enrolled, and MSCTPI was performed after 2 weeks post-cranioplasty. There were 12 cases in flap survival group and 12 cases in flap necrosis group. The data were analyzed by body perfusion software, and the BF, BV and TTP were statistically analyzed. Results: MSCTPI showed that the density of right occipital flaps in the necrotic group reduced, small slices of necrosis could be seen, and a part of flap was absent, the perfusions of right temporal and occipital flaps were low(blue areas); the density of flaps in survival group were in accordance with healthy sides, perfusion pseudo-maps of flap and healthy sides were of the same color, BF and BV of necrosis group reduced in comparison to that of survival group; TTP of necrosis group prolonged in comparison to that of survival group; there are significantly statistical differences in BF, BV and TTP between two groups. Conclusion: MSCTPI technology can quantitatively evaluate the survival of flaps after large-area cranioplasty. It provides a new clinical method to quantitatively evaluate blood supply of flaps.
		2018 Vol. 29 (11): 761-763 [Abstract] ( 286 ) HTML (1 KB) PDF (0 KB) ( 40 )

	764	The application of MR SWI in intracranial hemorrhage of neonatal hyperbilirubinemia
		GUO Li-li1, WANG De-hang2, ZHANG Hui1, TAO Wei-jing1, BO Gen-ji1
		DOI: 10.12117/jccmi.2018.11.002
		Objective: To explore the value and limitation of SWI compared with conventional MRI in intracranial hemorrhage patients with neonatal hyperbilirubinemia. Materials and Methods: We conducted a study including 120 neonates. All 120 neonatal cases received MRI and SWI scanning, two radiologists who don’t know the history of subjects analyzed MRI and SWI images by double blind method. We recorded the detection of hemorrhagic cases and numbers in routine MRI and SWI and analyzed the performances of the intracranial hemorrhage in different locations. Results: ①The detection rates of neonatal intracranial hemorrhage between MRI and SWI were statistically significant(P<0.001), SWI is superior to conventional MRI. In the high blood bilirubin group, the detection positive rates of bleeding in routine MRI and SWI were statistically significant(P<0.05), and in the normal control group, the detection positive rate of bleeding in routine MRI and SWI were not statistically significant(P>0.05).②Among 120 neonates there were 43 cases with intraeranial hemorrhage detected on routine MRI sequences and/or SWI. Among neonates with intraeranial hemorrhage there were 27 preterm and 16 term neonates; 29 neonates with high bilirubin and 14 cases of normal control. The differences of incidences between preterm infants and full term were statistically significant(P<0.05). Incidences of neonatal intracranial hemorrhage between high blood bilirubin group and normal control group were compared, differences were significant(P<0.05). ③Among 43 neonates with intracranial hemorrhage, there were only 14 cases showed extracerebral hemorrhage(8 cases subarachnoid hemorrhage(SAH), 5 cases subdural hemorrhage(SDH), 1 SDH combined with cerebral hemorrhage). All 14 cases were found in both MRI and SWI. The detection positive rates of extracerebral hemorrhage between MRI and SWI were not statistically significant(P>0.05). ④Twenty-nine cases were detected with intracerebral hemorrhage on SWI, and among them 10 cases did not be detected on conventional MRI sequences. Neonatal intracerebral hemorrhage included subependymal hemorrhage/intraventricular hemorrhage(PVH-IVH), intraparenchymal hemorrhage(IPH) and cerebellar hemorrhage(CH). The detection positive rates of PVH-IVH between conventional MRI and SWI did not show obvious statistical significance(P>0.05). The parenchymal hemorrhage(including IPH and CH) always showed the form of microbleeds(foci<10 mm), the detection positive rates of SWI were superior to conventional MRI, the differences were considered as statistically significant(P<0.05). ⑤Among 43 cases with intracranial hemorrhage 122 foci were detected, including 19(15.2%) PVH-IVH, 43(35.2%) IPH, 46(37.7%) CH, 6(4.9%) SDH and 8(6.8%) SAH on SWI. On conventional MRI 78 foci were detected. The comparison was statistically significant(P<0.05). ⑥In our study, the PVH-IVH was detected more among premature than full term infants. The IPH and CH were detected among preterm and full term infants. The SDH was detected more among full term infants and SAH was detected more among premature infants. Conclusion: The incidence of intracranial hemorrhage in premature infants with high blood bilirubin level is higher than normal control infants. SWI is superior to conventional MRI in the detection positive rates and focus numbers of parenchymal hemorrhage and can be used as a powerful supplement to conventional MRI.
		2018 Vol. 29 (11): 764-770 [Abstract] ( 354 ) HTML (1 KB) PDF (0 KB) ( 29 )

	771	The value of dual energy CT in Rhesus monkeys nonalcoholic fatty liver disease
		SUN Feng-jiao1, LIANG Zhi-gang1, YANG Zun-yuan1, TANG Chun-gui2, CHEN Zheng-li1, SHEN Yu-bo1, YAO Zun-wei1, WU Ming-ling1, CHEN Yuan-hai1, ZENG Wen1, GAO Fa-bao3
		DOI: 10.12117/jccmi.2018.11.003
		Objective: To evaluate dual energy CT(DECT) diagnostic ability on nonalcoholic fatty liver disease/steatohepatitis(NAFLD/NASH), by comparing the DECT results with histopathology. Materials and Methods: Seventy Rhesus monkeys(Age >7 years, BW >7 kg, HBV and HCV negative) underwent ultrasound examination, among them 19 monkeys with moderate steatosis and 12 with mild steatosis and 6 normal monkeys took DECT examination, and within two weeks after DECT, ultrasound guided biopsy was done on 10 moderate and 8 mild steatosis and 6 normal monkeys. Results: HU100 kVp/Sn140 kVp, ΔHUSn140-100 kVp and ΔHULv-Sp（50 keV） were 0.95±0.04, (2.8±2.1) HU, (-16.4±6.3) HU; 1.02±0.03, (-0.7±1.3) HU, (-6.8±5.0) HU and 1.11±0.01, (-6.2±0.4) HU, (7.5±1.8) HU respectively. These results showed strong correlation with histopathology(R=-0.57, P<0.01; R=0.54, P<0.01; R=-0.71, P<0.001). Conclusion: The diagnostic results of DECT and the pathological results have a good consistency. As a noninvasive method, DECT showed great capacity on NAFLD diagnosis.
		2018 Vol. 29 (11): 771-774 [Abstract] ( 339 ) HTML (1 KB) PDF (0 KB) ( 46 )

	775	Phase selection for observing washout appearance in diagnosing hepatocellular carcinoma in contrast enhanced CT and Gd-EOB-DTPA-enhanced MRI for chronic liver disease patients with normal liver function or Child-Pugh grade A
		FAN Lu-lu1, XIE Shuang-shuang2, ZHANG Kun2, LI Qing2, SHEN Wen2
		DOI: 10.12117/jccmi.2018.11.004
		Objective: To compare the diagnostic performance of washout appearance on portal venous phase or delayed phase(transitional phase) for hepatocellular carcinoma(HCC) between gadolinium-ethoxybenzyl-diethylenetriaminpentaacetic acid (Gd-EOB-DTPA)-enhanced MRI and contrast enhanced CT in patients with chronic liver disease and normal liver function or Child-Pugh grade A. Methods: Retrospective analysis of preoperative imaging data of patients with normal liver function or Child-Pugh grade A and pathologically confirmed HCC or non-HCC lesions from January 2015 to July 2017, including 83 patients with contrast enhanced CT and 54 patients with Gd-EOB-DTPA-enhanced MRI, was performed. The arterial phase enhancement and portal venous, and delayed/transitional phase washout appearance of each lesion were observed and recorded by two radiologists on the same workstation. The Mann-Whitney test was used to compare the differences in age and lesion size between contrast enhanced CT and Gd-EOB-DTPA-enhanced MRI groups. The Kappa test was used to analyze the consistency of characteristic evaluation of each lesion between two radiologists. The Chi-Square test or Fisher’s exact test was used to compare the sex distribution, pathological results, and arterial phase enhancement characteristic of different lesions. ROC curve was performed to compare the diagnostic performance of arterial phase enhancement combined with washout appearance in portal venous and delayed/transitional phase for HCC between two groups. Results: There was no statistical difference in the distribution of pathological results and the enhancement characteristics of arterial phase between the two groups(P all >0.05). In the contrast enhanced CT group, the AUC value of diagnosis HCC was 0.910 when the arterial phase enhancement combined with washout appearance on portal venous phase(sensitivity: 85.14%, specificity: 96.77%), and the AUC value was 0.849 when arterial phase enhancement combined with washout appearance on delayed phase(sensitivity: 89.19%, specificity: 80.65%), the difference of the AUC values was not statistically significant(P=0.089 0). In Gd-EOB-DTPA-enhanced MRI group, the AUC of diagnosing HCC value was 0.853 when the arterial phase enhancement combined with washout appearance of portal venous phase(sensitivity: 76.09%, specificity: 94.44%), and the AUC value was 0.729 when the arterial phase enhancement combined with washout appearance in transitional phase(sensitivity: 84.78%, specificity: 61.11%), and the difference of AUC values was statistically significant(P=0.043 1). Conclusion: In patients with chronic liver disease and normal liver function or Child-Pugh grade A, washout appearance observed on portal venous and delayed phase for HCC have similar diagnostic accuracy on contrast enhanced CT, but washout appearance observed on portal venous are more accurate than transitional phase on Gd-EOB-DTPA-enhanced MRI.
		2018 Vol. 29 (11): 775-781 [Abstract] ( 333 ) HTML (1 KB) PDF (0 KB) ( 41 )

	782	The value of the pixel shine algorithm in improving the display of small hepatocellular metastases in low single energy image with single-source dual-energy CT
		XU Ming-zhe1, LIU Ai-lian1, LIU Yi-jun1, LIU Jing-hong1, PAN Ju-dong2
		DOI: 10.12117/jccmi.2018.11.005
		Objective: To explore the value of pixel shine(PS) algorithm to improve the quality of single-energy image, especially the low single-energy image by single-source dual-energy CT, and to improve the detection of small liver metastases. Methods: Fourteen patients, who underwent spectral CT imaging using spectrum imaging modality(GSI) were retrospectively enrolled with 38 lesions in this study. The PS algorithm(A7 mode) was applied to process the low single-energy images obtained from the AW4.6 workstation to obtain four groups of 40~70 KeV single energy images before and after calculation by PS. The ROIs were draw in the liver metastases and normal liver parenchyma respectively at the same location and on the same slice, showing the maximum area of the lesion, of 40~70 KeV single-energy images by a senior radiologist, then CT and SD values were measured and recorded. The SNRs of liver metastases, the CNRs of liver metastases relative to normal liver parenchyma and the ratios of SNRs and CNRs in images after calculation by PS relative to before were calculated. The Shapiro-Wilk normal distribution test was used to check the normality of data. The CT values of liver metastases and normal liver parenchyma, SNRs and CNRs of hepatic metastases were compared between four groups of 40~70 KeV single energy images before and after calculation by PS, then the SNRs and CNRs of hepatic metastases in 40 KeV, 50 KeV and 60 KeV images processed by PS algorithm were compared with those in 70 KeV images. Paired samples t-test was used to compare the data that fit the normal distribution, and the Wilcoxon signed-rank test was used to compare the data that didn’t conform to normal distribution. The nonparametric Friedman test was used to compare the differences of SNR and CNR increase ratios of 40~70 KeV single energy images processed by PS algorithm. If there was a difference, the Wilcoxon signed rank test was used for comparison. Results: There were no differences between the CT values of liver metastases and liver parenchyma in four groups of 40~70 KeV single energy images before and after calculation by PS(P＞0.05). The SNR and CNR of liver metastases in 40~70 KeV single energy images processed by PS algorithm were greater than those in images without PS calculation(all P=0.000). Compared with SNRs and CNRs of hepatic metastases in 70 KeV PS images, the SNRs of hepatic metastases in 40 KeV images processed by PS was less than that in 70 KeV images without PS calculation, while the SNRs of hepatic metastases in 50 KeV and 60 KeV images processed by PS and the CNRs of liver metastases in 40 KeV, 50 KeV and 60 KeV images processed by PS were significantly greater than that in 70 KeV images without PS calculation. Conclusion: PS algorithm can significantly improve quality of single-energy images to show the intrahepatic metastasis lesion, and the PS algorithm used in the low single energy image has better effect on the display of lesions.
		2018 Vol. 29 (11): 782-787 [Abstract] ( 258 ) HTML (1 KB) PDF (0 KB) ( 42 )

	788	Texture analysis of CT images used to assess pathological grades of pancreatic neuroendocrine neoplasms
		YU Hao-peng, LI Mou, ZHANG Lin, YANG Cheng-min, ZHANG Yong-chang, SONG Bin
		DOI: 10.12117/jccmi.2018.11.006
		Objective: To evaluate the accuracy of the texture analysis to determinate the pathological grades of pancreatic neuroendocrine neoplasms(PNEN). Methods: 109 cases of pancreatic neuroendocrine neoplasms, confirmed by surgery or pathological biopsy, were retrospectively enrolled in our study. Both arterial phase and portal vein phase CT images of including patients were manual sketch the region of interest(ROI) by ITK Snap software. A.K. software was used for texture extraction, and R software with The least absolute shrinkage and selection operator(LASSO) was used for calculation. Results: In aterial phase, 5 texture features were selected, including maximum 3D diameter, kurtosis, GLCMEntropy_AllDirection_offset7_SD, quantile0.025 and Surface volume ratio, with AUROC of 0.715, 0.529, 0.724, 0.672 and 0.698, respectively. In portal vein phase, 2 texture features were selected including maximum 3D diameter and surface volume ratio, with AUROC of 0.722 and 0.703, respectively. Conclusions: Texture analysis of CT images can be used to evaluate the pathological classification of PNEN.
		2018 Vol. 29 (11): 788-791 [Abstract] ( 267 ) HTML (1 KB) PDF (0 KB) ( 29 )

	792	Value of Revolution CT perfusion imaging in differentiating adrenal lipid-poor adenoma and adrenal metastases of lung cancer
		ZHAO Ying, LIU Ai-lian, LIU Jing-hong, LIU Yi-jun, WANG Nan, FANG Xin
		DOI: 10.12117/jccmi.2018.11.007
		Objective: To investigate the value of Revolution CT perfusion imaging in differentiating adrenal lipid-poor adenoma(adenoma in short) and adrenal metastases of lung cancer(metastases in short). Materials and Methods: The data of adrenal Revolution CT perfusion scanning in our hospital were retrospectively collected, 13 cases of adenoma(CT value >10 HU) were pathologically confirmed, and 7 cases and 10 lesions of metastases were confirmed by clinical history and follow-up imaging. The size, unenhanced and enhanced CT attenuation numbers and perfusion parameter measurements(blood flow(BF), blood volume(BV), mean transit time(MTT), time to peak(TP) and permeability of surface(PS)) of tumors were recorded. Comparison of the above parameters between adenomas and metastases was tested. Receiver operating characteristic(ROC) curves were plotted to analyze diagnostic efficiency. Results: There was not statistical difference of length, minimum width, unenhanced CT value and enhanced CT values between adenoma and metastases group(all P>0.05). BF and BV values of adenoma were statistically higher than those of metastases(66.32±50.33 vs. (34.21±34.99) mL/(100 g·min), 18.81±5.93 vs. (8.06±5.44) mL/100 g, P=0.005 and 0.001, respectively), while there was not statistical difference of MTT, TP and PS values between the two tumors(P all>0.05). The area under the ROC curve of BF and BV values were 0.875 and 0.923, and there were a sensitivity of 92.3% and 75.0%, and a specificity of 84.6% and 100% for differentiating adenoma from metastases. Conclusion: It is difficult to identify adrenal lipid-poor adenoma and adrenal metastases of lung cancer by routine CT examination. However, BF and BV values can be used to identify both of them for higher diagnostic efficacy.
		2018 Vol. 29 (11): 792-797 [Abstract] ( 259 ) HTML (1 KB) PDF (0 KB) ( 30 )

	798	The diagnostic value of CT-based radiomics in liver metastasis of colorectal cancer
		GUO Yu1, LI Ming-yang2, LIU Xiang-chun1, WANG Ming-fei1, LI Xue-yan2, ZHANG Hui-mao1
		DOI: 10.12117/jccmi.2018.11.008
		Objective: To explore the predictive value of a CT-based radiomics for liver metastasis in colorectal cancer. Methods: In the retrospective study, 100 patients with pathologically confirmed by surgery to colorectal cancer and preoperative contrast-enhanced CT examination in the First Hospital of Jilin University from June to December 2017 were included(50 cases with liver metastasis; 50 cases without liver metastasis). The patients were divided into modeling group(80 cases) and testing group(20 cases) by computer random software according to the ratio of 4∶1. Using the software matlab 2017a and python to extract a list of radiomics features and construct the corresponding radiomics signature. The radiomics signature and clinical variable were included to establish multivariable random forest classifier(RFC) model that was simplified and validated. The efficiency of the model was evaluated by the method of hold-out and cross validation. Results: The discrimination of radiomics signature between the liver metastasis group and non-liver metastasis group is significant(P<0.05). The radiomics signature, carcinoembryonic antigen(CEA), carbohydrate antigen 19-9(CA19-9) expression were showed positive correlation with the liver metastasis of colorectal cancer(P<0.05). The RFC splits modeling group into training dataset and validation dataset as 7∶3, the accuracy is 81.5%, training dataset(AUC=0.991, sensitivity=84.0%, specificity=96.8%, positive predicted value=0.955, negative predictive value=0.882) and validation dataset(AUC=0.811, sensitivity=72.7%, specificity=92.3%, positive predicted value=0.889, negative predictive value=0.800). The accuracy in ten folded cross validation is 81.0%. The accuracy of testing group is 75.0%. Conclusion: The RFC model integrated with the radiomics signature based on CT imaging and clinical characteristic can be useful for diagnosis of liver metastasis in colorectal cancer.
		2018 Vol. 29 (11): 798-802 [Abstract] ( 282 ) HTML (1 KB) PDF (0 KB) ( 35 )

	803	Comparison of DCE-MRI parameters, modified Gleason score and PSA in predicting the risk of castration resistant prostate cancer in prostate cancer patients after treatment
		YAO Xiao-gang1, ZHU Pei-ju2, ZHAO Ming1, HUANG Yu-nong1, CHEN Jing1
		DOI: 10.12117/jccmi.2018.11.009
		Objective: To investigate the role of the DCE-MRI parameters, the modified Gleason score, and PSA in predicting the risk of castration resistant prostate cancer after prostate cancer treatment, and to provide evidence for clinical treatment. Methods: From August 2009 to August 2015, 193 patients with prostate cancer were treated in our hospital, and their age, DCE-MRI parameter, modified Gleason score, PSA, BMI and TNM staging were recorded. All patients were followed up for 2 years, the single factor analysis was used to analyzed the factors affecting the prognosis of patients with prostate cancer. The Cox regression model was used to further analyze the prognostic impact of prostate cancer on the severity of the disease. T test was used to show the differences in the distribution of prostate cancer risk factors between the two groups. The sensitivity and specificity of Ktrans and PSA levels in predicting the risk of castration resistant prostate cancer after treatment for prostate cancer were analyzed using the ROC curve. Results: Univariate analysis showed that age, improved Gleason score, PSA, DCE-MRI parameters, and TNM staging all affected the prognosis of the patients, and the difference was statistically significant(P<0.05). The results of Cox regression indicated that the DCE-MRI parameter, Ktrans value(P=0.027) and PSA value(P=0.028) had significant influence on the risk of CRPC, and the influence of Ktrans value was higher than that of PSA(RR=2.413 vs RR=2.012). The t test showed that the Ktrans value in the poor prognosis group was significantly higher than that in the good prognosis group(P=0.001). The level of PSA in the poor prognosis group was higher than that in the good prognosis group(P=0.024). Under the ROC curve, the AUC of Ktrans value was 0.843(95% confidence interval: 0.769 to 0.917), and the sensitivity and specificity were 82.14% and 71.43% respectively. The AUC of PSA level was 0.752(95% confidence interval: 0.657 to 0.847), and the sensitivity and specificity were 74.92% and 63.42% respectively. Conclusion: The DCE-MRI parameter Ktrans is a better predictor of CRPC in patients with prostate cancer after treatment and is expected to serve as a routine indicator of prostate cancer, to provide a basis for clinical treatment.
		2018 Vol. 29 (11): 803-807 [Abstract] ( 367 ) HTML (1 KB) PDF (0 KB) ( 37 )

	808	The value of multiple quantitative parameters of diffusion kurtosis imaging sequence to evaluate the expression of Ki-67 in endometrial carcinoma: a preliminary study
		TIAN Shi-feng, LIU Ai-lian, ZHU Wen, WANG Xue-dong, SONG Qing-wei, GUAN Hong-wei, LI Ye, LIU Jing-hong
		DOI: 10.12117/jccmi.2018.11.010
		Objective: To investigate the correlation between multiple quantitative parameters of diffusion kurtosis imaging sequence and the expression of proliferating antigen Ki-67 in endometrial carcinoma(EC). Methods: We retrospectively analyzed 21 cases of imaging data with 1.5T MRI examination(including DKI sequence) diagnosed as EC. The index of immunohistochemical analysis included Ki-67. According to the Ki-67 expression index(<50% was low expression, ≥50% was high expression), 21 cases were divided into Ki-67 high expression group(11 cases) and Ki-67 low expression group(10 cases). The DKI parameters of two groups were measured by two observers, included mean kurtosis(MK), axial kurtosis(Ka), radial kurtosis(Kr), fractional anisotropy of kurtosis(FAk), mean diffusivity(MD), axial diffusivity(Da), radial diffusivity(Dr) and fractional anisotropy(FA). The intra-class correlation coefficients(ICC) was used to test the consistency of the parameters measured results with the two observers. The two independent samples t test was used to compare the parameters of two groups. For the parameters that had the differential value, the ROC curve was used to evaluate their efficacy in the differential diagnosis of Ki-67 high and low expression groups. The Pearson correlation analysis was used to assess the correlation between the values of each parameter and Ki-67 expression index. Results: The data consistency of two observers was good(ICC>0.75). The MK, Ka, Kr, FAk, MD, Da, Dr and FA values of Ki-67 high expression group were 1.05±0.13, 1.17±0.21, 0.95±0.14, 0.41±0.14, (0.93±0.18) μm2/ms, (1.19±0.17) μm2/ms, (0.80±0.21) μm2/ms, 0.27±0.11, respectively. The parameters of Ki-67 low expression group were 0.79±0.10, 0.86±0.12, 0.72±0.14, 0.35±0.11, (1.33±0.28) μm2/ms, (1.64±0.37) μm2/ms, (1.17±0.25) μm2/ms, 0.23±0.08, respectively. The difference of MK, Ka, Kr, MD, Da and Dr values was statistically significant(P<0.05). The FAk, FA values of two groups were not statistically significant(P>0.05). The area under curve(AUC) of MK, Ka, Kr, MD, Da, Dr values to diagnose Ki-67 high expression were 0.982, 0.900, 0.900, 0.900, 0.973, 0.882, respectively. The boundary values were 0.92, 1.09, 0.85, 1.08 μm2/ms, 1.41 μm2/ms, 0.96 μm2/ms, respectively. The sensitivity was 90.9%, 72.7%, 81.8%, 81.8%, 100%, 81.8%, the specificity was 100%, 100%, 90%, 90%, 90%, 90%, respectively. The MK, Ka, Kr values were positively correlated with the Ki-67 expression index, the MD, Da, Dr values were negatively correlated with the Ki-67 expression index(P<0.05), and there were no correlation between the FAk and FA valueswith the Ki-67 expression index(P>0.05). Conclusion: The MK, Ka, Kr, MD, Da, Dr values of DKI sequence are related to the expression of Ki-67, and have the potential to reflect the proliferation of EC cells. MK value is the best parameter.
		2018 Vol. 29 (11): 808-813 [Abstract] ( 372 ) HTML (1 KB) PDF (0 KB) ( 38 )

	814	Analysis of bone metastasis screening by radiological examination for newly diagnosed patients with esophageal squamous carcinoma
		ZHENG Xiao-dong, ZHANG Wei-min, HOU Jian-bin
		DOI: 10.12117/jccmi.2018.11.011
		Objective: By analyzing the clinical characteristics of newly diagnosed 376 patients with esophageal squamous carcinoma, to evaluate the incidence of bone metastasis and discuss the necessity of bone scintigraphy for bone metastasis screening. Methods: We retrospectively reviewed the charts of 376 consecutive patients with a pathology diagnosis of esophageal squamous carcinoma in our department between March 2015 and June 2017, and evaluated gender, age, tumor location, TNM staging, and pain. Results: The rate of bone metastasis was 6.4%(24/376), the pain, M1, and agedness were significantly higher(P＜0.05) in positive patients with bone metastasis than negative patients, but no significant difference in gender, tumor location, cT, cN, cTNM staging(P＞0.005). Multivariate binary logistic regression analysis suggested that pain, M1,agedness were independent predictors of bone metastasis. Among 24 patients with bone metastasis, 29.2%(7/24) cases were Tis-2N0M0. Conclusions: For newly diagnosed patients with esophageal squamous carcinoma, bone metastasis may occur in patients with any cT, cN, cTNM and tumor location. Bone scintigraphy was necessary and the first preferred imageological examination for bone metastasis screening, especially for patients with M1, pain and advanced age.
		2018 Vol. 29 (11): 814-817 [Abstract] ( 290 ) HTML (1 KB) PDF (0 KB) ( 29 )

	818	The association between BMLs of the subchondral bone and stabilizer failure in knee joint
		WANG Jing1, CUI Jian-ling2, ZHAO Jian2, REN Jin-jun3, WANG Wei-xiu1
		DOI: 10.12117/jccmi.2018.11.012
		Objective: To explore the contribution of the stabilizing structures of the knee and other stress factors to the subchondral bone marrow edema-like lesions(BMLs) of the knee by evaluating the relationship between stabilizer failure of the subchondral bone and the BMLs of the knee. Methods: The stabilizer failure group with 281 cases and the normal structure group with 26 cases were tested by MR. MR images were graded by WORMS, including the cartilage, the meniscus, the ligaments(the anterior and posterior cruciate ligament, the medial and lateral collateral ligament), bone marrow edema. The presence of subchondral BMLs between the stabilizing structures defect and normal in the stabilizer failure group were compared and analyzed. The relationship between the meniscus tear or extrusion and the BMLs were tested by Rank correlation. The abnormality of the stabilizing structures and possible risk factors affected the size of subchondral BMLs were tested by logistic regression method. Results: The presence of BMLs was significantly higher in patients with stress changed group than normal structure group. The presence of BMLs was significantly higher in patients with cartilage defect than normal. The presence of BMLs was significantly higher in patients with the stabilizer ligaments tear than normal. The range of MFC BMLs is mainly affected by the anterior horn of the medial meniscus extrusion, and followed by the anterior horn of the medial meniscus tear, MFC cartilage defect and age. The range of MT BMLs is mainly affected by MT cartilage defect, and followed by the anterior horn of the medial meniscus tear and age. The range of LFC BMLs is mainly affected by LFC cartilage defect, and followed by the age. The range of LT BMLs is mainly affected by LT cartilage defect, and followed by the anterior horn of the lateral meniscus tear. The range of the gross BMLs is mainly affected by cartilage defect, and followed by the meniscus abnormality and age. Conclusion: Articular stabilizer structure defect would induce the formation of subchondral BMLs, and the main actor was the cartilage defect.
		2018 Vol. 29 (11): 818-821 [Abstract] ( 232 ) HTML (1 KB) PDF (0 KB) ( 37 )

	822	Evaluation of imaging appearances and differential diagnosis of spinal osteoid osteoma and osteoblastoma
		ZHANG Li-hua, YUAN Hui-shu, JIANG Liang, LIU Xiao-guang
		DOI: 10.12117/jccmi.2018.11.013
		Objective: To evaluate imaging characters of spinal osteoid osteoma and osteoblastoma and improve awareness of these tumors. Methods: Retrospectively analyze CT and MRI appearances of 40 patients with osteoid osteoma and osteoblastoma in spine confirmed by surgical operation and pathological diagnosis. All the patients were divided into two groups according to tumor diameter, and the comparation of imaging features was performed. Results: The diameter of tumors were less than 2 cm in 28 cases and 12 tumors were with diameter more than 2 cm. Twenty-six tumors were located in cervical spine, 5 in thoracic spine, 8 in lumbar spine and 1 in sacrum. Twenty-five tumors were located in vertebral accessory, 11 in vertebral body, 3 cases in lateral mass of C1 and 1 involved both vertebral body and accessory. Ossification of tumor nidus was seen in 35 tumors with 33 cases adjacent bone sclerosis and 30 sclerosis rim formation. Five cases were shown as lytic bone destruction. Fluid-fluid levels were seen in five cases. There was statistic difference in bone sclerosis and sclerosis rim between two groups. Conclusions: Spinal osteoid osteoma and osteoblastoma mainly were located in cervical spine and most of them in spinal face joints. Bone sclerosis and sclerosis rim made some sense in identifying these tumors. The diameter was one of diagnostic index.
		2018 Vol. 29 (11): 822-825 [Abstract] ( 439 ) HTML (1 KB) PDF (0 KB) ( 40 )

	826	Prediction research of cerebral infarction volume in acute ischemic stroke patients with middle cerebral artery occlusion by hyperintense vessel sign on FLAIR MRI
		XU Kai-xi, GU Bao-dong, MENG Yun, BIAN Guang-rong, XU Xing-ru, CHEN Yin-yi, ZHANG Yun
		DOI: 10.12117/jccmi.2018.11.014

		2018 Vol. 29 (11): 826-830 [Abstract] ( 355 ) HTML (1 KB) PDF (0 KB) ( 37 )

	829	The analysis of fast model CBCT for prostatic cancer radiation
		ZENG Hui1, PI Guo-liang2, CHENG Li-ping1, XU Yun-qing1, DENG Wei1, LAI Jian-jun3
		DOI: 10.12117/jccmi.2018.11.015

		2018 Vol. 29 (11): 829-831 [Abstract] ( 247 ) HTML (1 KB) PDF (0 KB) ( 42 )

	832	Primary intracranial malignant melanoma: a case report with MRI findings
		LV Qing-qing, ZHANG Yong, CHENG Jing-liang, WANG Wei-jian, XU Ke
		DOI: 10.12117/jccmi.2018.11.016

		2018 Vol. 29 (11): 832-833 [Abstract] ( 320 ) HTML (1 KB) PDF (0 KB) ( 31 )

	833	Rare diffuse thyroid cancer in children with multiple lymph node metastasis
		YIN Yue, LIU Lu-lun, CHEN Guang
		DOI: 10.12117/jccmi.2018.11.017

		2018 Vol. 29 (11): 833-834 [Abstract] ( 279 ) HTML (1 KB) PDF (0 KB) ( 43 )

	834	Myxoma of the lumbar spine: report of one case
		CAO Dong-liang, WANG Shan-jin, HU Tao, LU Li-ping, ZHAO Wei-dong, WU De-sheng
		DOI: 10.12117/jccmi.2018.11.018

		2018 Vol. 29 (11): 834-835 [Abstract] ( 269 ) HTML (1 KB) PDF (0 KB) ( 41 )

	836	Blue rubber bleb nevus syndrome: report of one case
		MU Ning-xia, YE Jian-jun, ZHANG Qiang, LIU Kang
		DOI: 10.12117/jccmi.2018.11.019

		2018 Vol. 29 (11): 836-836 [Abstract] ( 171 ) HTML (1 KB) PDF (0 KB) ( 46 )

Copyright © Editorial Board of JOURNAL OF CHINA MEDICAL IMAGING
Supported by:Beijing Magtech