Study of real-time three-dimensional echocardiography in the assessment of left ventricular systolicsynchronization in patients with hypertrophic cardiomyopathy
CHEN Jun-hong1, LI Dong-ye2, WANG Zhi-rong1, XU Tong-da1, ZHANG Yan-bin1
1. Department of Cardiology, the Affiliated Hospital of Xuzhou Medical College, Xuzhou Jiangsu 221000, China;2. Institute of Cardiovascular Disease, Xuzhou Medical College, Xuzhou Jiangsu 221000, China
Abstract：Objective: To assess left ventricular myocardial systolic dyssynchrony in patients with hypertrophic cardiomyopathy(HCM) by real-time three-dimensional echocardiography(RT3DE). Methods: Forty patients with HCM, 25 age and sex matched normal controls underwent examinations with 2D and full volume RT3DE. Ejection fraction was >0.55 in all subjects. According to with or without left ventricular outflow tract obstruction at rest, HCM patients were divided into 2 groups, non-obstructive HCM group and obstructive HCM group. With QLab 7.0 off-line software the 17 segmental volume-time curves were obtained. The difference(Dif) and standard deviation(SD) of the time to the point with minimal systolic volume(Tmsv) in 16, 12, and 6 segments were measured and adjusted by R-R interval(Tmsv Dif%, Tmsv SD%). Results: Compared with control group, the Tmsv 16-SD%, and there were no significant differences between non-obstructive and obstructive HCM group. The left ventricle volume-time curves of the HCM patients had disordered arrangement compared with the normal control. Conclusion: Systolic asynchrony is impaired in HCM patients with or without left ventricular outflow tract obstruction. The RT3DE is an useful method for detecting left ventricular dyssynchrony of HCM patients and provide additional value for understanding myocardial damage of HCM patients.
陈军红;李东野;王志荣;徐通达;张延斌. 实时三维超声心动图评价肥厚型心肌病患者左室收缩协调性研究[J]. , 2014, 25(7): 466-468.
CHEN Jun-hong;LI Dong-ye;WANG Zhi-rong;XU Tong-da;ZHANG Yan-bin. Study of real-time three-dimensional echocardiography in the assessment of left ventricular systolicsynchronization in patients with hypertrophic cardiomyopathy. , 2014, 25(7): 466-468.
2014, Vol. 25 
