Abstract:Objective: To investigate the differential diagnosis value of pulmonary atresia, persistent truncus arteriosus and aortic atresia by prenatal echocardiography, to improve the diagnostic rate of three kinds of diseases. Methods: We analyzed retrospectively 402 fetal hearts of congenital heart disease in our department. Twelve fetuses were diagnosed as the three kinds of diseases. Results: In all 12 fetuses, 7 fetuses were proved as persistent truncus arteriosus(one case misdiagnosed as pulmonary atresia), 2 fetuses with aortic atresia, 3 fetuses with pulmonary atresia. All of them were accompanied with other heart malformation. Conclusion: Echocardiography is the most important method to diagnose fetus with artery malformation. Although there are lots of common points among these three ultrasonographic performance, each of them has its own characteristics, which could be used for differential diagnosis. The difficulty is the differential diagnosis on pulmonary artery complete atresia and persistent truncus arteriosus.