Abstract：Objective: To evaluate the diagnostic performance of strain ultrasound elastography(UE) and diffused optical tomography(DOT) in the diagnosis of small breast cancer(≤2.00 cm). Methods: UE and DOT were performed on 112 breast lesions in 92 patients. Taking pathologic diagnosis as gold standard, receiver operating characteristic(ROC) curves were obtained to evaluate the diagnosis value of the two approaches. Results: There were 38 benign and 74 malignant lesions． Area under the curve of UE and DOT were 0.928(95%CI: 0.864～0.968) and 0.851(95%CI: 0.771～0.911), respectively. There was no significant differences(Z=1.698, P=0.089). The sensitivity, specificity and accuracy in the diagnosis of breast cancer for UE were 84.21%(32/38), 90.54%(67/74) and 88.39%(99/112), respectively. With a cutoff value of 131.88 μmol/L for the total tumor hemoglobin concentrations(TTHC), the sensitivity, specificity and accuracy for DOT were 86.84%(33/38), 82.43%(61/74) and 83.93%(94/112), respectively. Conclusion: UE and DOT are both useful for providing valuable reference for early diagnosis of small breast cancer(≤2.00 cm).
商 聪，李 晶，任卫东，郭 嵩，吕慧娜. 超声弹性成像与光散射断层成像诊断≤2.00 cm乳腺癌的对比研究[J]. 中国临床医学影像杂志, 2016, 27(4): 248-251.
SHANG Cong, LI Jing, REN Wei-dong, GUO Song, LV Hui-na. Contrastive study on ultrasound elastography and diffused optical tomography in the diagnosis of small breast cancer(≤2.00 cm). JOURNAL OF CHINA MEDICAL IMAGING, 2016, 27(4): 248-251.
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