Abstract:Objective: To investigate the MRI features of nonspecific mastitis and differential diagnosis between nonspecific mastitis and breast cancer. Methods: The MRI findings of 30 lesions of 29 cases with nonspecific mastitis confirmed by pathology from January 2013 to March 2016 were analyzed, and 20 breast cancer patients confirmed by pathology in the same period were randomly selected as control group, and the difference of MRI, DWI, DCE, EER, TIC and MIP findings between the two groups were compared. Result: In 30 lesions, 13 cases showed fat signal, all lesions showed high signal intensity on T2WI; 28 cases had ring reinforcement and enhanced separation, 29 cases showed high signal intensity on DWI, the mean value of ADC was (0.707±0.181)×10-3 mm2/s, and 53.3% of the cases were less than 0.700×10-3 mm2/s; 73.3% cases TIC was type Ⅰ. The mean value of EER was 123%±50%, 26 cases>80%, 4 cases≤80%. MIP: blood supply in 21 cases were increased. In 20 cases with breast cancer, 2 cases showed slightly high signal intensity on T2WI, 10 cases had centripetal and ring reinforced; all cases showed high signal intensity on DWI, the mean value of ADC was (0.874±0.108)×10-3 mm2/s, 2 cases<0.700×10-3 mm2/s, 85% cases TIC type Ⅱ~Ⅲ. The mean value of EER was 137%±36%, 19 cases>80%, 1 case≤80%; MIP: blood supply in 16 cases were increased, with ≤0.700×10-3 mm2/s for inflammatory lesions. The sensitivity, specificity and accuracy of ADC values respectively were 88.89%, 56.25% and 68% in inflammatory lesions, the differences were statistically significant between the two groups(χ2=6.74, P<0.01). TIC type Ⅰ was benign lesions while type Ⅱ and Ⅲ were malignant lesions. There were significant differences in TIC between the two groups(χ2=16.33, P<0.01). There was no significant difference in EER and MIP between the two groups(χ2=0.23(correction), P>0.05; χ2=0.62, P>0.05). Conclusion: MRI findings of nonspecific mastitis have certain characteristics. MRI plain scan combined with dynamic enhanced scan, morphology and hemodynamic parameters have important value in the differential diagnosis of breast cancer.
蒋国元,罗义云,柏拉拉,罗洪建. 非特异性乳腺炎的MRI表现及与乳腺癌的鉴别诊断[J]. 中国临床医学影像杂志, 2017, 28(11): 781-784.
JIANG Guo-yuan, LUO Yi-yun, BAI La-la, LUO Hong-jian. MRI findings and differential diagnosis of the nonspecific mastitis with breast cancer. JOURNAL OF CHINA MEDICAL IMAGING, 2017, 28(11): 781-784.