Assessment of left atrial global strain in different age healthy subjects using
three-dimensional speckle tracking imaging
ZHANG Yuan-mei1, LIN Hong2, FAN Rui2, LI Cui-ling2, YE Min2, YAO Feng-juan2
1. Department of Ultrasound, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, China;
2. Department of Ultrasound, the First Affiliated Hospital, Sun Yat-sen University, Institute of Diagnostic and
Interventional Ultrasound, Sun Yat-sen University, Guangzhou 510080, China
Abstract：Objective: To determine the left atrial(LA) function by examining the LA peak strains and time-to-peak strains using three-dimensional speckle tracking imaging(3D-STI) and explore its value in clinical application. Methods: A total of 194 volunteers were divided into adolescence, middle-aged and elderly groups according to their age. Apical four-chamber and two-chamber full-volume images were acquired in all subjects and analyzed by off-line 3D-STI analysis software. The global peak circumferential strain(GPCS), global peak longitudinal strain(GPLS), global peak area strain(GPAS), the time to peak circumferential strain(TGPCS), the time to peak longitudinal strain(TGPLS) and the time to peak area strain(TGPAS) of left atrium were obtained and compared, and then analyzed the correlation between these strains and left atrial total ejection fraction. Results: The LA global peak strains were significant decreased and TGPCS was significant increased in the elderly group when compared with the adolescence and middle-aged groups(P＜0.05); TGPLS and TGPAS were largely increased in the middle-aged group and elderly group compared to the adolescence group(P＜0.05), whereas for all the three global peak strains and TGPCS, no significant difference was found between the adolescence group and middle-aged group, also, there was no significant difference in TGPLS and TGPAS between the middle-aged group and elderly group. There was a good correlation between all the three global peak strains and left atrial ejection fraction. Conclusion: The 3D-STI technology can evaluate LA function in different age healthy adults, which has great importance in preventing and early monitoring subclinical cardiovascular disease.
张远妹1，林 红2，范 瑞2，李翠玲2，叶 敏2，姚凤娟2. 三维斑点追踪成像技术评价不同年龄段正常成人左房整体应变的研究[J]. 中国临床医学影像杂志, 2017, 28(11): 798-801.
ZHANG Yuan-mei1, LIN Hong2, FAN Rui2, LI Cui-ling2, YE Min2, YAO Feng-juan2. Assessment of left atrial global strain in different age healthy subjects using
three-dimensional speckle tracking imaging. JOURNAL OF CHINA MEDICAL IMAGING, 2017, 28(11): 798-801.
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