Abstract:Objective: To investigate MRI findings of lipid storage myopathy(LSM), and evaluate the clinical value of MRI for LSM. Materials and Methods: Nine cases with LSM proved by biopsy underwent MRI of pelvis and thigh, spin echo sequence, fast spin echo sequence and short tau inversion recovery(STIR) were used. Results: The signal intensity of diseased muscle in 8 cases with LSM was hyperintense on T2WI and T1WI, and hyperintense signal intensity on T2WI and iso-intense on T1WI was seen on 2 patients as well. One patient had no positive findings. Conclusion: The MRI findings in LSM show certain characteristics: the involved muscles show lipid storage findings symmetrically, and the necrotic-like signal can be seen in the active stage as well. MRI can provide objective data for clinical diagnosis, therapeutic evaluation and follow-up. It can also help to decide the accurate site for biopsy.