Abstract：Objective: To apply tissue synchronization imaging(TSI) to evaluate optimized cardiac resynchronization therapy(CRT). Methods: Thirty-two patients with optimized CRT were included. TSI and conventional echocardiography were performed before implantation, 1m, 3m, 6m after implantation. In apical 4, 2, 3 chamber plane, TSI index and the peak time difference were assessed. Conventional echocardiographic parameters included: LVEDD(left ventricular end-diastolic diameter）, LVESD(left ventricular end-systolic diameter), LVEF(left ventricular ejection fraction), MR area, mitral diastolic filling time(DFT), aortic VTI. Results: Compared with pre-implantation, TSI index and peak time difference were significantly reduced in pro 1m, pro 3m, pro 6m(P<0.05), LVEDD, LVESD, MR decreased progressively(P<0.05), while LVEF, DFT, VTI increased progressively(P<0.05). Conclusions: TSI allows quick evaluation of mechanical dyssynchrony and provides a reliable way to evaluate optimized CRT.
2008, Vol. 19 
