The study of relationship between ADC values and ages in different regions of normal prostate at different b values
ZHANG Fang-jing1, ZHU Ji-chao2, CHEN Yan-ping3
1.Department of Radiology, the Affiliated Shenzhen Maternity and Child Healthcare Hospital of SouthernMedical University, Shenzhen Guangdong 518028, China; 2.Department of Medical Imaging, LonggangCentral Hospital of Shenzhen, Shenzhen Guangdong 518116, China; 3.Medical Imaging Center,Nanfang Hospital, Southern Medical University, Guangzhou 510515, China
Abstract：Objective: To analyze and compare the changes of apparent diffusion coefficient(ADC) values of peripheral zone(PZ) and central gland(CG) in normal prostate gland and that of different age groups by 3.0T diffusion-weighted MR imaging(DWI) with array spatial sensitivity encoding(ASSET) technique at different b values. Methods: 29 patients who underwent prostate DWI scanning were enrolled in this study. These patients were divided into two groups as followed: young adult normal group(age from 21 to 50 years old), 14 cases; symptomless aged group(age from 51 to 79 years old), 15 cases. b values were 300, 600, 800 and 1 000 s/mm2. Results: The signal intensity of DWI and ADC values in the PZ were both higher than that in CG at the same b values in two groups. Statistically significant difference(P<0.05) was found in ADC values between PZ and CG. The signal intensity of DWI and ADC values of PZ and CG in the aged group were higher than that in the youth adult group at the same b value. Statistically significant difference(P<0.05) was found in ADC values at the same region. Statistically significant difference(P<0.05) was found in ADC values among four different b values at the same region. The lower the ADC values were, the larger the b values were. Positive correlations existed between age and the ADC values of PZ and CG significantly. Conclusion: The ADC values of PZ are higher than that in CG in normal prostate at the same b value. The higher the b values are, the lower the ADC values are. The ADC values of PZ in prostate increased as age increased. Age should be considered when prostatic diseases were diagnosed with ADC values.
张方璟;朱记超;陈燕萍. 不同b值时正常前列腺ADC值变化与年龄相关性研究[J]. , 2015, 26(1): 34-37.
ZHANG Fang-jing;ZHU Ji-chao;CHEN Yan-ping. The study of relationship between ADC values and ages in different regions of normal prostate at different b values. , 2015, 26(1): 34-37.
2015, Vol. 26 
