Abstract:Objective: To investigate the interventional recanalized therapeutic strategy and efficacy of occlusive lesion in iliac-femoral arteries. Materials and Methods: During Feb 2001 to Feb 2006, 42 patients(30 male and 12 female) whose arterial occlusive lesions in iliac artery and/or femoral artery had been diagnosed by DSA accepted interventional therapies. Among the 42 patients, the length of occlusive arteries ranged from 2cm to 30cm, the interval between symptom emerging and interventional therapeutic beginning ranged from 10 hours to 30 years. The interventional therapeutic tools included local thrombolytic therapy through endoarterial catheter, artery recanalization by guide wire, PTA and stent. Results: Immediate technical success was 97.6% (41/42 cases). The arterial occlusions were resolved successfully (local thrombolytic therapy in 26 cases, recanalization by guide wire in 31 cases, PTA in 33 cases and 60 stents in 31 cases). There were no severe complications(such as angiorrhexis, perforation) during interventional process. The symptoms of lower limb ischemia were palliated or vanished in all patients and ABI increased from 0.34±0.14 to 0.65±0.095(P<0.001) after interventional therapy. During the follow-up (24 months), 11/42 (23.2%) occlusions of an iliac or femoral stent occurred (treated with local intra-arterial thrombolysis, PTA and stent). One patient died of myocardial infarct 15 months post-operation. Conclusions: Interventional recanalized therapy is an effective and safe therapy for occlusive lesion in iliac-femoral arteries.