Assessment of radionuclide scanning in 310 pulmonary carcinoma patients with bone metastasis
ZHANG Ke1, KONG Xiang-hui1, WU Zhi-xing1, LV Kuan1, SHEN Chao1, LIU Chun-yu1, LIU Jia-lin2
1. Department of Nuclear Medicine, Shandong Provincial Hospital, Shandong University, Jinan 250021, China; 2. Worker Hospital of Jinan Boiler Group Co., LTD, Jinan 250023, China
Abstract：Objective: To evaluate the characteristics of radionuclide bone imaging in pulmonary carcinoma patients with bone metastasis. Methods: Radionuclide bone scan by double gantre SPECT were performed in 310 pulmonary carcinoma patients with bone metastasis, and local imaging were performed when necessary. Results: The bone metastasis is most common in patients with adenocarcinoma of lung(64.83%). Most metastatic foci were seen in bones of the rib(263 cases). Multiple abnormal radionuclide concentration were seen in 250 patients(80.6%), and 60 patients with only one foci(19.3%). Conclusion: The bone metastasis could be detected 3～6 months earlier using radionuclide bone scan, which is the method of choice for diagnosing bone metastasis, other than X-ray and CT. The incidence of bone metastasis in peripheral lung cancer is higher than in central lung cancer, which suggests that the bone metastasis is associated with the primary site of the cancer and the onset time of clinical symptoms. And the prognosis of the patient is related to the number of bone metastatic foci in radionuclide bone imaging.
2008, Vol. 19 
