Abstract：Objective: To investigate the clinical usefulness of DTI multiple parameter and diffusion tenser tracting(DTT) in astrocytomas. Methods: Thirty-three cases of astrocytomas underwent routine MRI, enhanced scanning and DTI before and/or after operation. DCavg, FA, 1-VR and RA values were measured in the solid part of tumors, the necrotic area, the peritumoral edema, the white matter area surrounding the edema and corresponding normal brain; and the white matter surrounding tumors were rebuilt with DTT. Results: The white matter of brain could be seen better in FA and DTI graph, and not in routine MRI. There was significant difference of ADC, DCavg, FA, 1-VR and RA values in the solid part of tumors, the necrotic area, the peritumoral edema and the white matter area surrounding the edema. The peritumoral white matter of most low-grade astrocytoma cases were displaced, while of high-grade astrocytomas were destroyed. Conclusion: Combined with conventional MR imaging, DCavg, FA, 1-VR and RA values were conduced to distinguish the solid part of tumors, the necrotic area, the peritumoral edema and the white matter area surrounding the edema in distinguishing astrocytoma grade; FA, 1-VR, and RA value were conduced to detect low-grade and high-grade astrocytomas. DTI and DTT can be used to select the better operation methods and evaluate effect of operation.
孙夕林;王 丹;申宝忠;李 琳;何琦玮;刘 芳. DTI多参数综合分析在颅内星形细胞瘤临床分级及神经外科手术中的应用价值研究[J]. , 2009, 20(9): 677-680.
SUN Xi-lin;WANG Dan;SHEN Bao-zhong;LI Lin;HE Qi-wei;LIU Fang. The clinical and surgical application of DTI multiple parameter value and DTT in astrocytomas. , 2009, 20(9): 677-680.
2009, Vol. 20 
