Abstract：Objective: To observe the perfusion characteristics of contrast-enhanced ultrasound(CEUS) in renal cell carcinoma(RCC) by a new contrast agent SonoVue, and to analyze the pathological characteristics of RCC after operation. Methods: Forty-two cases of RCC were examined by the CEUS before operation, we observed the beginning of contrast agent enhancement, the peak and the dissipation as a whole, and analyzed the time-intensity curve(TIC) with ACQ software. Results: Twenty-eight clear cell renal cell carcinoma(CCRCC) cases showed rich blood supply, the results of TIC showed ΔAT and ΔTTP were smaller than the other two groups, the ΔPI and ΔI60s were significantly higher than the other two groups, that was “fast-in and slow-out and high enhance” contrast mode. Other 3 CCRCC cases, all the chromophobe carcinomas and papillary carcinomas showed low blood supply performance. The AT and TTP of chromophobe carcinomas and papillary carcinomas were slower than the surrounding renal tissue, the PI and I60s were lower than the surrounding renal tissue, that was “slow-in and low enhance” contrast characteristics. Conclusion: Real-time CEUS can provide more micro-perfusion characteristics in RCC. It provides more reference of the diagnosis and differential diagnosis in RCC, which has a higher clinical value.
2010, Vol. 21 
